[Back]
Assoz. Prof. Mag. Dr. Anna Weinzinger, Privatdoz.
T: +43-1-4277-55311
61 - 72 out of 72
Karmazinova M, Beyl S, Weinzinger A, Suwattanasophon C, Klugbauer N, Hering S et al. Cysteines in the loop between IS5 and the pore helix of Ca(V)3.1 are essential for channel gating: Cysteines in the loop between IS5 and the pore helix of Ca(V)3.1 are essential for channel gating. Pflügers Archiv: European Journal of Physiology. 2010;460(6):1015-1028. doi: 10.1007/s00424-010-0874-5
de Boer T, Nalos L, Weinzinger A, Kok B, Houtman MJC, Antoons G et al. The anti-protozoal drug pentamidine blocks KIR2.x-mediated inward rectifier current by entering the cytoplasmic pore region of the channel. British Journal of Pharmacology. 2010;159(7):1532-1541. doi: 10.1111/j.1476-5381.2010.00658.x
Thai KM, Windisch A, Stork D, Weinzinger A, Schiesaro A, Guy HR et al. The hERG potassium channel and drug trapping: insights from docking studies with propafenone derivatives: The hERG potassium channel and drug trapping: insight from docking studies with propafenone derivatives. ChemMedChem: chemistry enabling drug discovery. 2010;5(3):436-442. doi: 10.1002/cmdc.200900374
Weinzinger A, Wacker SJ, Boukharta L, Zachariae U, Karimi-Nejad Y, Aqvist J et al. Toward a Consensus Model of the hERG Potassium Channel. ChemMedChem: chemistry enabling drug discovery. 2010;5(3):455-467. doi: 10.1002/cmdc.200900461
Kudrnac M, Beyl S, Hohaus A, Weinzinger A, Peterbauer T, Timin E et al. Coupled and independent contributions of residues in IS6 and IIS6 to activation gating of CaV1.2. Journal of Biological Chemistry. 2009;284(18):12276-12284.
Knape K, Beyer A, Weinzinger A, Buchbauer G, Wolschann KP. Evolutionary trace of human odorant receptors of chromosome 17. Flavour & Fragrance Journal. 2009;24(4):192-197. doi: 10.1002/ffj.1933
Knape K, Beyer A, Weinzinger A, Buchbauer G, Wolschann KP. Genomics of selected human odorant receptors. Monatshefte für Chemie. 2008;139(12):1537-1544. doi: 10.1007/s00706-008-0957-6
Weinzinger A, Kudrnac M, Beyl S, Hohaus A, Timin E, Wolschann KP et al. Molecular dynamics and mutational analysis of a channelopathy mutation in the IIS6 helix of Ca(V)1.2. Channels (Austin). 2008;2(3):116-223. doi: 10.4161/chan.2.3.6160
Hering S, Beyl S, Weinzinger A, Kudrnac M, Hohaus A, Guy HR et al. Pore stability and gating in voltage-activated calcium channels. Channels (Austin). 2008;2:61-69. doi: 10.4161/chan.2.2.5999
Weinzinger A, Guy HR, Shafrir Y, Hering S, Wolschann KP. Structural model of the Ca(V)1.2 pore. Channels (Austin). 2008;2(3):210-215.
Buchbauer G, Suwattanasophon C, Weinzinger A, Wolschann KP. Differences in (-)citronellal binding to various odorant receptors. Biochemical and Biophysical Research Communications. 2007;361(4):941-945.
Hering S, Kudrnac M, Timin E, Hohaus A, Weinzinger A, Beyl S et al. Probing the architecture of an L-type calcium channel with a charged phenylalkylamine: Evidence for a widely open pore and drug trapping. Journal of Biological Chemistry. 2007;3864-3870.
61 - 72 out of 72

When regulation fails: Allosteric coupling in GIRK channels from Keppen–Lubinsky to GNB1 encephalopathy

Weinzinger, A. (Speaker)

15 Apr 2026

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Allosteric control of GIRK channels: insights from channelopathies and drug modulation

Weinzinger, A. (Speaker)

Mar 2026

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Ion Channels in Health and Disease: From Mechanistic Understanding to Therapeutic Solutions

Weinzinger, A. (Speaker)

16 Sept 2025

Activity: Talks and presentations › Talk or oral contribution › Science to Science

GNB1: Mutations, Protein Interactions, and Drug Repurposing

Weinzinger, A. (Speaker)

24 Jun 2025

Activity: Talks and presentations › Talk or oral contribution › Science to Public

GIRK2 DRUG REPURPOSING SCREEN IDENTIFIES TREATMENT OPTIONS FOR PATIENTS SUFFERING FROM EXTREMELY RARE DISEASES

Netzer, M. (Speaker), Hering, S. (Contributor), Dascal, N. (Contributor) & Weinzinger, A. (Contributor)

16 Feb 2025

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Allosteric mechanisms of inward rectifier K+ channel gating probed by disease mutants and ethosuximide

Weinzinger, A. (Speaker)

12 Sept 2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Allosteric regulation of GIRK K+ channels

Weinzinger, A. (Speaker)

9 Jul 2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Allosteric mechanisms of inward rectifier K+ channel gating

Weinzinger, A. (Speaker)

23 Jun 2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Challenges in drug repurposing for rare diseases – the GNB1/KCNJ6 example

Weinzinger, A. (Speaker)

12 Sept 2023

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Probing Inward Rectifier K+ Channel Gating and Conductance Guided by Disease Mutations

Weinzinger, A. (Speaker)

21 Jun 2023

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Computational investigation of a rare disease

Friesacher, T. (Speaker) & Weinzinger, A. (Contributor)

Sept 2022 → …

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Visualizing individual protonation events in Kir2 channels

Jirout, M. (Speaker), Zangerl-Plessl, E. M. (Contributor) & Weinzinger, A. (Contributor)

Sept 2022 → …

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Computational investigations of ion channels

Weinzinger, A. (Speaker)

15 Sept 2019 → 20 Sept 2019

Activity: Talks and presentations › Talk or oral contribution › Science to Science

FASEB: The Ion Channel Regulation Conference: Molecules to Disease

Weinzinger, A. (Speaker)

7 Jul 2019 → 12 Jul 2019

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Structure-dynamics-function relationships of inward rectifier K+ channels probed by in silico methods

Weinzinger, A. (Speaker)

27 Mar 2018

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Computational investigations of cation channels

Weinzinger, A. (Speaker)

19 May 2017

Activity: Talks and presentations › Talk or oral contribution › Science to Science

In silico modelling and drug interactions in Kir6.1

Weinzinger, A. (Speaker)

4 Oct 2016

Activity: Talks and presentations › Talk or oral contribution › Other

Molecular modeling of Cantu Syndrome Channels

Weinzinger, A. (Speaker)

10 Sept 2015

Activity: Talks and presentations › Talk or oral contribution › Other

Computational investigations of hERG K+ channels

Weinzinger, A. (Speaker)

10 Aug 2015

Activity: Talks and presentations › Talk or oral contribution › Other

MD SIMULATIONS OF KIRBAC1.1 MUTANTS REVEAL GATING CHANGES AT THE BUNDLE CROSSING REGION

Weinzinger, A. (Speaker)

4 Feb 2013

Activity: Talks and presentations › Talk or oral contribution › Other

Investigating the structural basis of hERG channel block guided by molecular dynamics simulations

Weinzinger, A. (Speaker)

25 Sept 2012

Activity: Talks and presentations › Talk or oral contribution › Other

In silico modelling of Kir2.x channels

Weinzinger, A. (Speaker)

2011 → …

Activity: Talks and presentations › Talk or oral contribution › Science to Science

IK1 block by small molecules

Weinzinger, A. (Speaker)

2010 → …

Activity: Talks and presentations › Talk or oral contribution › Other

In silico prediction of the cardiotoxicity of drug candidates

Weinzinger, A. (Speaker)

2008 → …

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Modelling the hERG K+ channel

Weinzinger, A. (Speaker)

2008 → …

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Towards a consensus model of the hERG K+ channel

Weinzinger, A. (Speaker)

2008 → …

Activity: Talks and presentations › Talk or oral contribution › Other

Computer modeling strategies to investigate the molecular basis of odor discrimination

Weinzinger, A. (Speaker)

2006 → …

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Novel approaches to investigate the regulation of G-protein coupled inward rectifier K+ channels by Gβγ

Weinzinger, A. (Project Lead) & Friesacher, T. (Co-Lead)

1/08/21 → 31/07/24

Project: Research funding

PROSTAGLANDINES - POTENTIAL THERAPEUTICS FOR DEND SYNDROME?

Weinzinger, A. (Project Lead)

1/12/20 → 30/07/23

Project: Research funding

Sulfonylharnstoffe

Weinzinger, A. (Project Lead)

1/03/15 → 28/02/19

Project: Research funding

hERG K+ Channel activators

Weinzinger, A. (Project Lead)

4/11/14 → 4/11/15

Project: Research funding

hEAG1 channel blockers

Weinzinger, A. (Project Lead)

15/03/14 → 14/03/15

Project: Research funding

Molecular Drug Targets

Hering, S. (Project Lead), Ecker, G. (Co-Lead), Maulide, N. (Co-Lead), Weinzinger, A. (Co-Lead) & Gonzalez Herrero, L. (Co-Lead)

1/12/10 → 31/12/22

Project: Research funding

hERG potassium channel

Weinzinger, A. (Project Lead)

27/10/10 → 31/12/11

Project: Research funding

Department of Pharmaceutical Sciences

Josef-Holaubek-Platz 2 (UZA II)
1090 Wien
Room: 2D178

T: +43-1-4277-55311

anna.stary@univie.ac.at