Einzelansicht Zille

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Assoz. Prof. Marietta Zille, BSc MSc PhD

T: +43-1-4277-55313

marietta.zille@univie.ac.at

https://pharmtox.univie.ac.at/research/cerebrovascular-pharmacology-prof-zille/

Summer term 2026

321014 VO Anatomie und Physiologie - B8

321020 VO Einführung in die allgemeine Pharmakologie und Pharmakokinetik - B11

321037 VU Pharmazeutische Wissenschaften - B20

322005 VO (Bio)pharmazeutika mit Wirkung auf das Herz-Kreislauf System - M4

322027 VU Ausgewählte Kapitel aus der pharmakologischen Forschung - M13

322086 VU Drugs, Diet, and Digital Myths: Identifying and Countering Medical Misinformation - M14

322087 VO 3R (Replacement-Reduction-Refinement)-Konzepte für den optimierten Einsatz von Tierversuchen - M14

323007 UE Experimental Methods in Drug Discovery und Preclinical Drug Development - MPS6 - (2 Courses)

580003 SE Academic Journey Club

Winter term 2025

322001 VO (Bio)pharma. mit Wirkung auf metabol. Störungen & eingeschr. Organ- und Systemfunktionen - M1

322002 VO Antiinfektiva, Antineoplastika und (Bio)pharmazeutika mit Wirkung auf das Immunsystem - M2

322089 VU Dietary effects on brain health - M14

Summer term 2025

321014 VO Anatomie und Physiologie - B8

321020 VO Einführung in die allgemeine Pharmakologie und Pharmakokinetik - B11

322005 VO (Bio)pharmazeutika mit Wirkung auf das Herz-Kreislauf System - M4

322027 VU Ausgewählte Kapitel aus der pharmakologischen Forschung - M13

322087 VO 3R (Replacement-Reduction-Refinement)-Konzepte für den optimierten Einsatz von Tierversuchen - M14

Mortimer KRH, Vernon-Browne H, Zille M, Didwischus N, Boltze J. Potential effects of commonly applied drugs on neural stem cell proliferation and viability: A hypothesis-generating systematic review and meta-analysis. Frontiers in molecular neuroscience. 2022 Oct 5;15:975697. doi: 10.3389/fnmol.2022.975697

Gutiérrez-Ospina G, Perez-Cruz C, Zenaro E, Zille M. Editorial: Neurodegenerative Diseases: Looking Beyond the Boundaries of the Brain. Frontiers in Neuroscience. 2022 Jun 23;16:929786. doi: 10.3389/fnins.2022.929786

Zille M, Oses-Prieto JA, Savage SR, Karuppagounder SS, Chen Y, Kumar A et al. Hemin-Induced Death Models Hemorrhagic Stroke and Is a Variant of Classical Neuronal Ferroptosis. The Journal of Neuroscience. 2022 Mar 9;42(10):2065-2079. Epub 2022 Jan 5. doi: 10.1523/JNEUROSCI.0923-20.2021

Zille M, Plesnila N, Boltze J. Pharmacologically targeting inflammation and improving cerebrospinal fluid circulation improves outcome after subarachnoid haemorrhage. EBioMedicine. 2022 Mar 1;77:103937. doi: 10.1016/j.ebiom.2022.103937

Maluje Y, Zille M. Integrating phase-contrast and fluorescence microscopy data for the analysis of axonal degeneration in a model of intracerebral hemorrhage using deep learning. In Student Conference Proceedings 2022. Lübeck: ‎ Infinite Science Publishing. 2022

Zille M, Farr TD, Keep RF, Römer C, Xi G, Boltze J. Novel targets, treatments, and advanced models for intracerebral haemorrhage. EBioMedicine. 2022 Feb 11;76:103880. doi: 10.1016/j.ebiom.2022.103880

Winek K, Zanatta DC, Zille M. Brain–body communication in stroke: Mens sana in corpore sano. Neuroforum. 2021 Dec 20;28(1):31-39. doi: 10.1515/nf-2021-0030

Wenzel J, Lampe J, Müller-Fielitz H, Schuster R, Zille M, Müller K et al. The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells. Nature Neuroscience. 2021 Nov 21;24(11):1522–1533. doi: 10.1038/s41593-021-00926-1

Dörschmann P, Apitz S, Hellige I, Neupane S, Alban S, Kopplin G et al. Evaluation of the Effects of Fucoidans from Fucus Species and Laminaria hyperborea against Oxidative Stress and Iron-Dependent Cell Death. Marine Drugs. 2021 Sept 29;19(10):557. doi: 10.3390/md19100557

Palumbo A, Gruening P, Landt SK, Heckmann LE, Bartram L, Pabst A et al. Deep Learning to Decipher the Progression and Morphology of Axonal Degeneration. Cells. 2021 Sept 25;10(10):2539. doi: 10.3390/cells10102539

Krueger K, Boehme E, Klettner AK, Zille M. The potential of marine resources for retinal diseases: a systematic review of the molecular mechanisms. Critical Reviews in Food Science and Nutrition. 2021 May 10;62(27):7518-7560. Epub 2021 May 10. doi: 10.1080/10408398.2021.1915242

Boltze J, Aronowski JA, Badaut J, Buckwalter MS, Caleo M, Chopp M et al. New Mechanistic Insights, Novel Treatment Paradigms, and Clinical Progress in Cerebrovascular Diseases. Frontiers in Aging Neuroscience. 2021 Jan 28;13:623751. doi: 10.3389/FNAGI.2021.623751

Auer N, Zille M. Detection of Axonal Degeneration in Microscopic Image Time Series using a Deep Learning Approach. In Buzug TM, editor, Student Conference Proceedings 2021 : 10th Conference on Medical Engineering Science, 6th Conference on Medical Informatics, 4th Conference on Biomedical Engineering, 3rd Conference on Auditory Technology, 1st Conference on Biophysics, 1st Conference on Robotics and Autonomous Systems : Lübeck, March 10-12, 2021. Lübeck: ‎ Infinite Science Publishing. 2021. p. 341-344

Grüning P, Palumbo A, Landt SK, Heckmann L, Brackhagen L, Zille M et al. Robust and Markerfree in vitro Axon Segmentation with CNNs. In Ye J, O’Grady MJ, Civitarese G, Yordanova K, editors, Wireless Mobile Communication and Healthcare - 9th EAI International Conference, MobiHealth 2020, Proceedings. 1. ed. Cham: Springer International Publishing. 2021. p. 274-284. (Lecture Notes of the Institute for Computer Sciences Social Informatics and Telecommunications Engineering, Vol. 362). doi: 10.1007/978-3-030-70569-5_17

Riabinska A, Zille M, Terzi MY, Cordell R, Nieminen-Kelhä M, Klohs J et al. Correction to: Pigment Epithelium-Derived Factor Improves Paracellular Blood–Brain Barrier Integrity in the Normal and Ischemic Mouse Brain. Cellular and Molecular Neurobiology. 2020 Jul 1;40(5):765-766. doi: 10.1007/s10571-020-00872-9

Riabinska A, Zille M, Terzi MY, Cordell R, Nieminen-Kelhä M, Klohs J et al. Pigment Epithelium-Derived Factor Improves Paracellular Blood–Brain Barrier Integrity in the Normal and Ischemic Mouse Brain. Cellular and Molecular Neurobiology. 2020 Jul 1;40(5):751-764. doi: 10.1007/s10571-019-00770-9

Menon NK, Palumbo A, Gruening P, Landt SK, Heckmann LE, Bartram L et al. Segmentation of fluorescently labelled axons in a model of brain hemorrhage-induced axonal degeneration using convolutional neural networks. In Buzug TM, editor, Student Conference Proceedings 2020: 9th Conference on Medical Engineering Science, 5th Conference on Medical Informatics, 3rd Conference on Biomedical Engineering, 2nd Conference on Auditory Technology : Lübeck, March 3-5, 2020. Lübeck: ‎ Infinite Science Publishing. 2020. p. 229-232

Boltze J, Ferrara F, Hainsworth AH, Bridges LR, Zille M, Lobsien D et al. Lesional and perilesional tissue characterization by automated image processing in a novel gyrencephalic animal model of peracute intracerebral hemorrhage. Journal of Cerebral Blood Flow & Metabolism. 2019 Dec 21;39(12):2521-2535. doi: 10.1177/0271678X18802119

Zille M, Ikhsan M, Jiang Y, Lampe J, Wenzel J, Schwaninger M. The impact of endothelial cell death in the brain and its role after stroke: A systematic review. Cell Stress. 2019 Nov 11;3(11):330-347. doi: 10.15698/cst2019.11.203

Ikhsan M, Palumbo A, Rose D, Zille M, Boltze J. Neuronal Stem Cell and Drug Interactions: A Systematic Review and Meta‐Analysis: Concise Review. Stem Cells Translational Medicine. 2019 Nov 1;8(11):1202-1211. doi: 10.1002/sctm.19-0020