Univ.-Prof. Dr. Verena Dirsch
Verena Dirsch
1 - 20 out of 209

Haiss P, Liu R, Xian F, Varela DG, Schmidt M, Dirsch VM et al. Evodiamine induces centrosome amplification with subsequent G2/M cell cycle arrest in primary vascular smooth muscle cells. Biochemical Pharmacology. 2025 Sept 9;242(Pt 2):117320. Epub 2025 Sept 9. doi: 10.1016/j.bcp.2025.117320

Schwarz PF, Perhal AF, Guder F, Hernández González JE, Janssen K, Sağıroğlu E et al. Identification of New Lupane-Type Triterpenoids as Inverse Agonists of RAR-Related Orphan Receptor Gamma (RORγ). Journal of Natural Products. 2025 Aug 22;88(8):1887-1900. doi: 10.1021/acs.jnatprod.5c00416

Baumann A, Freutsmiedl V, Jelleschitz J, Staltner R, Brandt A, Schachner D et al. Honokiol, a Neolignan from Magnolia officinalis, Attenuated Fructose-Induced Hepatic Fat Accumulation by Improving Intestinal Barrier Function in Mice. The Journal of Nutrition. 2025 Apr;155(4):1173-1182. doi: 10.1016/j.tjnut.2025.02.017

Cannavacciuolo C, Napolitano A, Dirsch VM, Heiss EH, Masullo M, Piacente S. Oleraceins from Portulaca oleracea leaves: Quali-quantitative determination and antioxidant potential. Current Research in Food Science. 2025 Jan 30;10:100992. Epub 2025 Jan 30. doi: 10.1016/j.crfs.2025.100992

Perhal AF, Papadopoulos MGE, Medel-Lacruz B, Ladurner A, Selent J, Dirsch V et al. Discovery and characterization of small-molecule TGR5 ligands with agonistic activity. European Journal of Medicinal Chemistry. 2024 Oct 5;276:116616. doi: 10.1016/j.ejmech.2024.116616

Czollner L, Papaplioura E, Linder T, Liu R, Li Y, Atanasov AG et al. A silver-coated copper wire as inexpensive drug eluting stent model: determination of the relative releasing properties of leoligin and derivatives. Monatshefte fur Chemie. 2023 Dec;154(12):1317-1326. Epub 2020 Nov 5. doi: 10.1007/s00706-020-02677-4

He Z, Zhang Z, Xu P, Dirsch VM, Wang L, Wang K. Laminarin Reduces Cholesterol Uptake and NPC1L1 Protein Expression in High-Fat Diet (HFD)-Fed Mice. Marine Drugs. 2023 Dec;21(12):624. doi: 10.3390/md21120624

Resetar M, Tietcheu Galani BR, Tsamo AT, Chen Y, Schachner D, Stolzlechner S et al. Flindissone, a Limonoid Isolated from Trichilia prieuriana, Is an LXR Agonist. Journal of Natural Products. 2023 Aug 25;86(8):1901-1909. doi: 10.1021/acs.jnatprod.3c00059

Zwirchmayr J, Schachner D, Grienke U, Rudžionytė I, de Martin R, Dirsch VM et al. Biochemometry identifies suppressors of pro-inflammatory gene expression in Pterocarpus santalinus heartwood. Phytochemistry. 2023 Aug;212:113709. doi: 10.1016/j.phytochem.2023.113709



Blažević T, Ciotu CI, Gold-Binder M, Heiss EH, Fischer MJM, Dirsch VM. Cultured rat aortic vascular smooth muscle cells do not express a functional TRPV1. PLoS ONE. 2023 Feb;18(2):e0281191. doi: 10.1371/journal.pone.0281191

Rollinger JM, Langeder J, Grienke U, Kirchweger B, Wasilewicz A, Dirsch V et al., inventors. Sanggenon for antiviral treatment. WO2023280767. 2023.

Cannavacciuolo C, Napolitano A, Heiss EH, Dirsch VM, Piacente S. Portulaca oleracea, a rich source of polar lipids: Chemical profile by LC-ESI/LTQOrbitrap/MS/MSn and in vitro preliminary anti-inflammatory activity. Food Chemistry. 2022 Sept 15;388:132968. doi: 10.1016/j.foodchem.2022.132968


Pferschy-Wenzig EM, Ortmann S, Atanasov AG, Hellauer K, Hartler J, Kunert O et al. Characterization of Constituents with Potential Anti-Inflammatory Activity in Chinese Lonicera Species by UHPLC-HRMS Based Metabolite Profiling. Metabolites. 2022 Apr;12(4):288. doi: 10.3390/metabo12040288

Linder T, Papaplioura E, Ogurlu D, Geyrhofer S, Hummelbrunner S, Schachner D et al. Investigation of Leoligin Derivatives as NF-κΒ Inhibitory Agents. Biomedicines. 2022 Jan;10(1):62. Epub 2021 Dec 28. doi: 10.3390/biomedicines10010062

Hou X, Malainer C, Atanasov AG, Heiß EH, Dirsch VM, Wang L et al. Evodiamine Lowers Blood Lipids by Up-Regulating the PPARγ/ABCG1 Pathway in High-Fat-Diet-Fed Mice. Journal of Natural Products. 2021 Dec 24;84(12):3110-3116. doi: 10.1021/acs.jnatprod.1c00881

Ladurner A, Schwarz P, Dirsch V. Natural products as modulators of retinoic acid receptor-related orphan receptors (RORs). Natural Product Reports - NPR. 2021 Apr;38(4):757-781. Epub 2020 Oct 29. doi: 10.1039/D0NP00047G

1 - 20 out of 209

2D NMR-based biochemometric approach for natural product research: fishing bioactives out of multicomponent mixtures

Adelsberger, S. (Speaker), Perhal, A. F. (Contributor), Bertaina, L. (Contributor), Schwarz, P. (Contributor), Dirsch, V. (Contributor), Rollinger, J. M. (Contributor) & Grienke, U. (Contributor)

1 Sept 2025

Activity: Talks and presentationsTalk or oral contributionScience to Science


2D NMR-based biochemometrics for deciphering bioactive compounds in multicomponent herbal mixtures

Adelsberger, S. (Speaker), Perhal, A. F. (Contributor), Bertaina, L. (Contributor), Schwarz, P. (Contributor), Dirsch, V. (Contributor), Rollinger, J. M. (Contributor) & Grienke, U. (Contributor)

3 Jul 2025

Activity: Talks and presentationsTalk or oral contributionScience to Science


Nuclear receptors as targets for natural product (analogs).

Dirsch, V. (Invited speaker)

30 Jun 202530 Jun 2028

Activity: Talks and presentationsTalk or oral contributionScience to Science


Nuclear receptors as targets for natural product (analogs).

Dirsch, V. (Invited speaker)

7 Nov 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Nukleäre Rezeptoren als Targets für Naturstoffe und deren Analoga.

Dirsch, V. (Invited speaker)

15 May 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


RXR and ROR as targets for natural products and structural analogs.

Dirsch, V. (Speaker)

3 Nov 20235 Nov 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


RXR and ROR as targets for natural products and structural analogs.

Dirsch, V. (Speaker)

23 Oct 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


RXR and ROR as targets for natural product (analogs).

Dirsch, V. (Speaker)

4 Sept 20237 Sept 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


RXR and ROR as targets for natural products and structural analogs.

Dirsch, V. (Speaker)

1 Dec 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Impulse lecture: career options in academia.

Dirsch, V. (Speaker) & Rollinger, J. M. (Speaker)

19 May 202220 May 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Einfluss des Neolignans Honokiol auf die intestinale Barrierefunktion

Baumann, A. (Speaker), Habersatter, E. (Contributor), Schachner, D. (Contributor), Dirsch, V. (Contributor) & Bergheim, I. (Contributor)

17 Mar 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Neolignan analogs lead to a selective RXR modulator.

Dirsch, V. (Speaker)

24 Sept 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


From man to mice to molecules.

Dirsch, V. (Speaker)

5 Apr 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Discovery of new GPBAR1 agonists by combined in silico - in vitro screening

Kirchweger, B. (Speaker), Müller Kratz, J. (Contributor), Ladurner, A. (Contributor), Grienke, U. (Contributor), Dirsch, V. (Contributor), Langer, T. (Contributor) & Rollinger, J. M. (Contributor)

26 Aug 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Neolignan derivatives as RXR selective modulators – A promising approach against metabolic disease?

Dirsch, V. (Speaker)

12 Jun 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Neolignan-derived rexinoids: promising modulators in metabolic disease?

Dirsch, V. (Speaker)

2 May 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Neolignan-derived rexinoids: promising modulators in metabolic disease?

Dirsch, V. (Speaker)

19 Apr 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Das Berufsbild des Hochschullehrers im Wandel, Symposium: Hochschullehrer 2030 – endangered species or global player.

Dirsch, V. (Speaker)

20 Oct 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


Pharmacognosy and Pharmacology: two sides of one coin?

Dirsch, V. (Speaker)

30 Sept 2016

Activity: Talks and presentationsTalk or oral contributionOther


From man to mice to molecules.

Dirsch, V. (Speaker)

16 May 2016

Activity: Talks and presentationsTalk or oral contributionOther


RXRα and neolignans – a promising approach against metabolic disease?

Dirsch, V. (Speaker)

11 Apr 2016

Activity: Talks and presentationsTalk or oral contributionOther


Bioactives from Natural Sources – a Vienna perspective.

Dirsch, V. (Speaker)

7 Oct 2015

Activity: Talks and presentationsTalk or oral contributionOther


Bioactives from Natural Sources – new opportunities using approaches from molecular biology.

Dirsch, V. (Speaker)

16 Oct 2014

Activity: Talks and presentationsTalk or oral contributionOther


Neolignans: from PPARγ to RXRα

Dirsch, V. (Speaker)

25 Sept 2014

Activity: Talks and presentationsTalk or oral contributionOther


Biosimilars.

Dirsch, V. (Speaker)

24 May 2014

Activity: Talks and presentationsTalk or oral contributionOther


Natural products in vascular biology - molecular mechanisms.

Dirsch, V. (Invited speaker)

22 Nov 2012

Activity: Talks and presentationsTalk or oral contributionOther


Natural products as leads and tools in cardiovascular research.

Dirsch, V. (Invited speaker)

4 Oct 2012

Activity: Talks and presentationsTalk or oral contributionOther


Leads and Lessons from Natural Products.

Dirsch, V. (Invited speaker)

12 Dec 2011

Activity: Talks and presentationsTalk or oral contributionOther


Naturstoffe in der Gefäßbiologie – Molekulare Wirkmechanismen.

Dirsch, V. (Invited speaker)

1 Dec 2011

Activity: Talks and presentationsTalk or oral contributionOther


Bioactive natural products targeting inflammation.

Dirsch, V. (Invited speaker)

23 Sept 2011

Activity: Talks and presentationsTalk or oral contributionOther


Natural products as leads and tools in cardiovascular research.

Dirsch, V. (Invited speaker)

16 Jun 2011

Activity: Talks and presentationsTalk or oral contributionOther


Natural products and redox regulation.

Dirsch, V. (Invited speaker)

15 Jul 2010

Activity: Talks and presentationsTalk or oral contributionOther


Effect of roscovitine and derivatives in PDGF-activated VSMC.

Dirsch, V. (Invited speaker)

14 Jun 2010

Activity: Talks and presentationsTalk or oral contributionOther


Natural products as leads and tools in cardiovascular research

Dirsch, V. (Invited speaker)

20 Nov 2009

Activity: Talks and presentationsTalk or oral contributionOther


Leads and Lessons from Nature

Dirsch, V. (Invited speaker)

17 Oct 2009

Activity: Talks and presentationsTalk or oral contributionOther


Naturstoffe in der Gefäßbiologie – molekulare Wirkmechanismen

Dirsch, V. (Speaker)

21 Jul 2009

Activity: Talks and presentationsTalk or oral contributionOther


Virtual and real screening of natural products to find effective modulators of protein tyrosine phosphatase PTP1B.

Dirsch, V. (Contributor)

18 Apr 2009

Activity: Talks and presentationsTalk or oral contributionOther


Natural products – leads and lessons

Dirsch, V. (Speaker)

3 Mar 2009

Activity: Talks and presentationsTalk or oral contributionOther


Vasoprotection by inhibition of vascular smooth muscle cell growth and migration.

Dirsch, V. (Invited speaker)

18 Jul 2008

Activity: Talks and presentationsTalk or oral contributionOther


Natural product-driven chemical biology: a useful concept for target identification?

Dirsch, V. (Invited speaker)

11 Jul 2008

Activity: Talks and presentationsTalk or oral contributionOther


Leads and lessions from natural products.

Dirsch, V. (Invited speaker)

5 May 2008

Activity: Talks and presentationsTalk or oral contributionOther


Austrian red wines and their effects on endothelial nitric oxide synthase

Dirsch, V. (Contributor)

25 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


Antioxidantien, pflanzliche Polyphenole: was können Rotwein und Co?

Dirsch, V. (Invited speaker)

26 Oct 2007

Activity: Talks and presentationsTalk or oral contributionOther


Gefäßschutz durch Zellwachstumshemmung - vom Naturstoff zum Target

Dirsch, V. (Invited speaker)

10 Oct 2007

Activity: Talks and presentationsTalk or oral contributionOther


Natural products and chronic inflamnmatory vascular processes.

Dirsch, V. (Invited speaker)

2 Sept 2007

Activity: Talks and presentationsTalk or oral contributionOther


Selective inhibition of platelet-derived growth factor-induced signalling cascades by indirubin-3'-monoxime

Dirsch, V. (Contributor)

2 Sept 2007

Activity: Talks and presentationsTalk or oral contributionOther


Chronic resveratrol induces a redox- dependent senescent-like growth arrest - role of the S-phase arrest

Dirsch, V. (Contributor)

13 Mar 2007

Activity: Talks and presentationsTalk or oral contributionOther


Effects of indirubin-3`-monoxime on platelet-derived growth factor signaling

Dirsch, V. (Contributor)

6 Sept 2006

Activity: Talks and presentationsTalk or oral contributionOther


Natural products: small molecule tools to probe for pharmacological targets?

Dirsch, V. (Contributor)

18 Nov 2005

Activity: Talks and presentationsTalk or oral contributionOther


Rotwein - die angenehme Art dem Herzinfarkt vorzubeugen ?

Dirsch, V. (Speaker)

18 Oct 2005

Activity: Talks and presentationsTalk or oral contributionOther


Naturstoffe - nicht nur ideal zur Wirkstoff- sondern auch zur Targetsuche?

Dirsch, V. (Contributor)

20 Jun 2005

Activity: Talks and presentationsTalk or oral contributionOther


Mit einem Naturstoff auf Target-Suche: Shp2, ein Hemmer vaskulärer Hypertrophie?

Dirsch, V. (Contributor)

28 Jan 2005

Activity: Talks and presentationsTalk or oral contributionOther


Rotweinpolyphenole - die angenehme Art dem Herzinfarkt vorzubeugen?

Dirsch, V. (Contributor)

26 Oct 2004

Activity: Talks and presentationsTalk or oral contributionOther


Resveratrol hemmt die Angiotensin II-induzierte Hypertrophie in vaskulären glatten Muskelzellen - aber über welches Target?

Dirsch, V. (Contributor)

28 Jun 2004

Activity: Talks and presentationsTalk or oral contributionOther


Polyphenole aus dem Rotwein - eine Erklärung für das "French Paradox"?

Dirsch, V. (Contributor)

25 May 2004

Activity: Talks and presentationsTalk or oral contributionOther


Mittels Resveratrol von der Angiotensin II-induzierten Hypertrophie zur Phosphatase Shp2

Dirsch, V. (Contributor)

24 May 2004

Activity: Talks and presentationsTalk or oral contributionOther


Resveratrol: Einfluss auf Proliferation/Zellzyklus und die Angiotensin II-induzierte Hypertrophy von vaskulären glatten Muskelzellen.

Dirsch, V. (Contributor)

21 Apr 2004

Activity: Talks and presentationsTalk or oral contributionOther


NO French Paradox without red wine polyphenols?

Dirsch, V. (Contributor)

31 Mar 2004

Activity: Talks and presentationsTalk or oral contributionOther


Naturstoffe als Tools?: was uns Resveratrol über das Angiotensin II Signaling in vaskulären glatten Muskelzellen erzählt......

Dirsch, V. (Contributor)

28 Jan 2004

Activity: Talks and presentationsTalk or oral contributionOther


Resveratrol and other cardiovascular active natural products.

Dirsch, V. (Contributor)

19 Jun 2003

Activity: Talks and presentationsTalk or oral contributionOther


Resveratrol: Einfluss auf Proliferation und Zellzyklus von vaskulären glatten Muskelzellen

Dirsch, V. (Contributor)

4 Jun 2003

Activity: Talks and presentationsTalk or oral contributionOther


Resveratrol: Mechanismen der Wachstumshemmung von vaskulären glatten Muskelzellen

Dirsch, V. (Contributor)

28 Apr 2003

Activity: Talks and presentationsTalk or oral contributionOther


Mechanism of vascular smooth muscle cell growth arrest by resveratrol

Dirsch, V. (Contributor)

22 Apr 2003

Activity: Talks and presentationsTalk or oral contributionOther


Einfluss von Resveratrol auf Zellzyklus und Proliferation von vaskulären glatten Muskelzellen

Dirsch, V. (Contributor)

9 Apr 2003

Activity: Talks and presentationsTalk or oral contributionOther


Resveratrol: Mechanismen der Wachstumshemmung von glatten Muskelzellen

Dirsch, V. (Contributor)

16 Dec 2002

Activity: Talks and presentationsTalk or oral contributionOther


Vasoprotective compounds made by nature?

Dirsch, V. (Contributor)

27 Jun 2002

Activity: Talks and presentationsTalk or oral contributionOther



Resveratrol, eine vielversprechende Substanz zur Prävention von Atherosklerose?

Dirsch, V. (Contributor)

10 Dec 2001

Activity: Talks and presentationsTalk or oral contributionOther


Cell-based techniques for the discovery and characterisation of anti-inflammatory natural products

Dirsch, V. (Invited speaker)

8 Oct 2001

Activity: Talks and presentationsTalk or oral contributionOther


Das Triterpen-Chinonmethid Pristimerin hemmt die Induktion der induzierbaren NO-Synthase in LPS-aktivierten RAW 264.7 Makrophagen

Dirsch, V. (Invited speaker)

2 Dec 1998

Activity: Talks and presentationsTalk or oral contributionOther


Der Einfluß von Allicin und Ajoen. zwei Verbindungen aus dem Knoblauch, auf die induzierbare NO-Synthase

Dirsch, V. (Speaker)

8 May 1998

Activity: Talks and presentationsTalk or oral contributionOther


Der RXR-Ligand LRK071 - Mechanismus und Funktion

Dirsch, V. (Project Lead)

1/01/2231/12/25

Project: Research funding


TMC-VASC

Dirsch, V. (Project Lead)

1/07/1230/06/14

Project: Research funding


Good practice in TCM

Dirsch, V. (Project Lead), Kopp, B. (Co-Lead) & Szabo, A. (Admin)

1/05/0931/10/12

Project: Research funding


Drugs from Nature Targeting Inflammation

Kopp, B. (Project Lead) & Dirsch, V. (Project Lead)

1/04/0831/03/11

Project: Research funding


Resveratrol

Dirsch, V. (Project Lead)

1/07/0630/06/09

Project: Research funding


Protein Kinase Research

Dirsch, V. (Project Lead)

1/03/0628/02/09

Project: Research funding


Department of Pharmaceutical Sciences

Deputy Head

Josef-Holaubek-Platz 2 (UZA II)
1090 Wien
Room: 2G452

T: +43-1-4277-55270

verena.dirsch@univie.ac.at