ao. Univ.-Prof. Mag. Dr. Michael Wirth

Josef-Holaubek-Platz 2 (UZA II)
1090 Wien
Room: 2F307

T: +43-1-4277-55407
michael.wirth@univie.ac.at

Photo of Michael Wirth

Research

Research Group with Franz Gabor: Smart Drug Delivery

Wheat germ agglutinin (WGA) is a dietary lectin that adheres to the mucus as well as the membrane of absorptive cells and it is taken up into the cells. For smart drug delivery the question arises whether WGA can carry drug delivery systems as a backpack like a “Sherpa” to or into absorptive cells.

By mimicking the adhesion of uropathogenic E. coli on the urothelium, smart nanopharmaceuticals consisting of a drug loaded core and a WGA-corona, a new strategy for treatment of urinary tract infections and cancer by instillative administration is currently investigated.

Publications: 


PhD students

Alexander Hämmerli