Univ.-Prof. Dr. Verena Dirsch
Verena Dirsch
1 - 20 out of 202
Czollner L, Papaplioura E, Linder T, Liu R, Li Y, Atanasov AG et al. A silver-coated copper wire as inexpensive drug eluting stent model: determination of the relative releasing properties of leoligin and derivatives. Monatshefte fur Chemie. 2023 Dec;154(12):1317-1326. Epub 2020 Nov 5. doi: 10.1007/s00706-020-02677-4

He Z, Zhang Z, Xu P, Dirsch VM, Wang L, Wang K. Laminarin Reduces Cholesterol Uptake and NPC1L1 Protein Expression in High-Fat Diet (HFD)-Fed Mice. Marine Drugs. 2023 Dec;21(12):624. doi: 10.3390/md21120624

Resetar M, Tietcheu Galani BR, Tsamo AT, Chen Y, Schachner D, Stolzlechner S et al. Flindissone, a Limonoid Isolated from Trichilia prieuriana, Is an LXR Agonist. Journal of Natural Products. 2023 Aug 25;86(8):1901-1909. doi: 10.1021/acs.jnatprod.3c00059

Zwirchmayr J, Schachner D, Grienke U, Rudžionytė I, de Martin R, Dirsch VM et al. Biochemometry identifies suppressors of pro-inflammatory gene expression in Pterocarpus santalinus heartwood. Phytochemistry. 2023 Aug;212:113709. doi: 10.1016/j.phytochem.2023.113709



Blažević T, Ciotu CI, Gold-Binder M, Heiss EH, Fischer MJM, Dirsch VM. Cultured rat aortic vascular smooth muscle cells do not express a functional TRPV1. PLoS ONE. 2023 Feb;18(2):e0281191. doi: 10.1371/journal.pone.0281191



Pferschy-Wenzig E-M, Ortmann S, Atanasov AG, Hellauer K, Hartler J, Kunert O et al. Characterization of Constituents with Potential Anti-Inflammatory Activity in Chinese Lonicera Species by UHPLC-HRMS Based Metabolite Profiling. Metabolites. 2022 Apr;12(4):288. doi: 10.3390/metabo12040288

Linder T, Papaplioura E, Ogurlu D, Geyrhofer S, Hummelbrunner S, Schachner D et al. Investigation of Leoligin Derivatives as NF-κΒ Inhibitory Agents. Biomedicines. 2022 Jan;10(1):62. Epub 2021 Dec 28. doi: 10.3390/biomedicines10010062

Hou X, Malainer C, Atanasov AG, Heiß EH, Dirsch VM, Wang L et al. Evodiamine Lowers Blood Lipids by Up-Regulating the PPARγ/ABCG1 Pathway in High-Fat-Diet-Fed Mice. Journal of Natural Products. 2021 Dec 24;84(12):3110-3116. doi: 10.1021/acs.jnatprod.1c00881

Ladurner A, Schwarz P, Dirsch V. Natural products as modulators of retinoic acid receptor-related orphan receptors (RORs). Natural Product Reports - NPR. 2021 Apr;38(4):757-781. Epub 2020 Oct 29. doi: 10.1039/D0NP00047G

Atanasov AG, Zotchev SB, Dirsch VM, the International Natural Product Sciences Taskforce, Supuran CT. Natural products in drug discovery: advances and opportunities. Nature Reviews Drug Discovery. 2021 Mar;20:200-216. Epub 2021 Jan 28. doi: 10.1038/s41573-020-00114-z


Ladurner A, Linder T, Wang L, Hiebl V, Schuster D, Schnürch M et al. Characterization of a structural leoligin analog as farnesoid X receptor agonist and modulator of cholesterol transport. Planta Medica. 2020 Oct 1;86(15):1097-1107. doi: 10.1055/a-1171-8357

Dao-Huy T, Latkolik S, Bräuer J, Pfeil A, Stuppner H, Schnürch M et al. Structural features defining nf-κb inhibition by lignan-inspired benzofurans and benzothiophenes. Biomolecules. 2020 Aug;10(8):1131. doi: 10.3390/biom10081131

Wang D, Hiebl V, Schachner D, Ladurner A, Heiss EH, Atanasov AG et al. Soraphen A enhances macrophage cholesterol efflux via indirect LXR activation and ABCA1 upregulation. Biochemical Pharmacology. 2020 Jul;177:114022. doi: 10.1016/j.bcp.2020.114022

Zwirchmayr J, Grienke U, Hummelbrunner S, Seigner J, de Martin R, Dirsch VM et al. A biochemometric approach for the identification of in vitro anti-inflammatory constituents in masterwort. Biomolecules. 2020 May;10(5):679. doi: 10.3390/biom10050679

Resetar M, Liu X, Herdlinger S, Kunert O, Pferschy-Wenzig E-M, Latkolik S et al. Polyacetylenes from Oplopanax horridus and Panax ginseng: Relationship between Structure and PPARγ Activation. Journal of Natural Products. 2020 Apr 24;83(4):918-926. doi: 10.1021/acs.jnatprod.9b00691

1 - 20 out of 202

RXR and ROR as targets for natural products and structural analogs.

Verena Dirsch (Speaker)

3 Nov 20235 Nov 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


RXR and ROR as targets for natural products and structural analogs.

Verena Dirsch (Speaker)

23 Oct 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


RXR and ROR as targets for natural product (analogs).

Verena Dirsch (Speaker)

4 Sep 20237 Sep 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


RXR and ROR as targets for natural products and structural analogs.

Verena Dirsch (Speaker)

1 Dec 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Impulse lecture: career options in academia.

Verena Dirsch (Speaker) & Judith Maria Rollinger (Speaker)

19 May 202220 May 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Einfluss des Neolignans Honokiol auf die intestinale Barrierefunktion

Anja Baumann (Speaker), Elisabeth Habersatter (Contributor), Daniel Schachner (Contributor), Verena Dirsch (Contributor) & Ina Bergheim (Contributor)

17 Mar 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Neolignan analogs lead to a selective RXR modulator.

Verena Dirsch (Speaker)

24 Sep 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


From man to mice to molecules.

Verena Dirsch (Speaker)

5 Apr 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Discovery of new GPBAR1 agonists by combined in silico - in vitro screening

Benjamin Kirchweger (Speaker), Jadel Müller Kratz (Contributor), Angela Ladurner (Contributor), Ulrike Grienke (Contributor), Verena Dirsch (Contributor), Thierry Langer (Contributor) & Judith Maria Rollinger (Contributor)

26 Aug 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Neolignan derivatives as RXR selective modulators – A promising approach against metabolic disease?

Verena Dirsch (Speaker)

12 Jun 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Neolignan-derived rexinoids: promising modulators in metabolic disease?

Verena Dirsch (Speaker)

2 May 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Neolignan-derived rexinoids: promising modulators in metabolic disease?

Verena Dirsch (Speaker)

19 Apr 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Das Berufsbild des Hochschullehrers im Wandel, Symposium: Hochschullehrer 2030 – endangered species or global player.

Verena Dirsch (Speaker)

20 Oct 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


Pharmacognosy and Pharmacology: two sides of one coin?

Verena Dirsch (Speaker)

30 Sep 2016

Activity: Talks and presentationsTalk or oral contributionOther


From man to mice to molecules.

Verena Dirsch (Speaker)

16 May 2016

Activity: Talks and presentationsTalk or oral contributionOther


RXRα and neolignans – a promising approach against metabolic disease?

Verena Dirsch (Speaker)

11 Apr 2016

Activity: Talks and presentationsTalk or oral contributionOther


Bioactives from Natural Sources – a Vienna perspective.

Verena Dirsch (Speaker)

7 Oct 2015

Activity: Talks and presentationsTalk or oral contributionOther


Bioactives from Natural Sources – new opportunities using approaches from molecular biology.

Verena Dirsch (Speaker)

16 Oct 2014

Activity: Talks and presentationsTalk or oral contributionOther


Neolignans: from PPARγ to RXRα

Verena Dirsch (Speaker)

25 Sep 2014

Activity: Talks and presentationsTalk or oral contributionOther


Biosimilars.

Verena Dirsch (Speaker)

24 May 2014

Activity: Talks and presentationsTalk or oral contributionOther


Natural products in vascular biology - molecular mechanisms.

Verena Dirsch (Invited speaker)

22 Nov 2012

Activity: Talks and presentationsTalk or oral contributionOther


Natural products as leads and tools in cardiovascular research.

Verena Dirsch (Invited speaker)

4 Oct 2012

Activity: Talks and presentationsTalk or oral contributionOther


Leads and Lessons from Natural Products.

Verena Dirsch (Invited speaker)

12 Dec 2011

Activity: Talks and presentationsTalk or oral contributionOther


Naturstoffe in der Gefäßbiologie – Molekulare Wirkmechanismen.

Verena Dirsch (Invited speaker)

1 Dec 2011

Activity: Talks and presentationsTalk or oral contributionOther


Bioactive natural products targeting inflammation.

Verena Dirsch (Invited speaker)

23 Sep 2011

Activity: Talks and presentationsTalk or oral contributionOther


Natural products as leads and tools in cardiovascular research.

Verena Dirsch (Invited speaker)

16 Jun 2011

Activity: Talks and presentationsTalk or oral contributionOther


Natural products and redox regulation.

Verena Dirsch (Invited speaker)

15 Jul 2010

Activity: Talks and presentationsTalk or oral contributionOther


Effect of roscovitine and derivatives in PDGF-activated VSMC.

Verena Dirsch (Invited speaker)

14 Jun 2010

Activity: Talks and presentationsTalk or oral contributionOther


Natural products as leads and tools in cardiovascular research

Verena Dirsch (Invited speaker)

20 Nov 2009

Activity: Talks and presentationsTalk or oral contributionOther


Leads and Lessons from Nature

Verena Dirsch (Invited speaker)

17 Oct 2009

Activity: Talks and presentationsTalk or oral contributionOther


Naturstoffe in der Gefäßbiologie – molekulare Wirkmechanismen

Verena Dirsch (Speaker)

21 Jul 2009

Activity: Talks and presentationsTalk or oral contributionOther


Virtual and real screening of natural products to find effective modulators of protein tyrosine phosphatase PTP1B.

Verena Dirsch (Contributor)

18 Apr 2009

Activity: Talks and presentationsTalk or oral contributionOther


Natural products – leads and lessons

Verena Dirsch (Speaker)

3 Mar 2009

Activity: Talks and presentationsTalk or oral contributionOther


Vasoprotection by inhibition of vascular smooth muscle cell growth and migration.

Verena Dirsch (Invited speaker)

18 Jul 2008

Activity: Talks and presentationsTalk or oral contributionOther


Natural product-driven chemical biology: a useful concept for target identification?

Verena Dirsch (Invited speaker)

11 Jul 2008

Activity: Talks and presentationsTalk or oral contributionOther


Leads and lessions from natural products.

Verena Dirsch (Invited speaker)

5 May 2008

Activity: Talks and presentationsTalk or oral contributionOther


Austrian red wines and their effects on endothelial nitric oxide synthase

Verena Dirsch (Contributor)

25 Apr 2008

Activity: Talks and presentationsTalk or oral contributionOther


Antioxidantien, pflanzliche Polyphenole: was können Rotwein und Co?

Verena Dirsch (Invited speaker)

26 Oct 2007

Activity: Talks and presentationsTalk or oral contributionOther


Gefäßschutz durch Zellwachstumshemmung - vom Naturstoff zum Target

Verena Dirsch (Invited speaker)

10 Oct 2007

Activity: Talks and presentationsTalk or oral contributionOther


Natural products and chronic inflamnmatory vascular processes.

Verena Dirsch (Invited speaker)

2 Sep 2007

Activity: Talks and presentationsTalk or oral contributionOther


Selective inhibition of platelet-derived growth factor-induced signalling cascades by indirubin-3'-monoxime

Verena Dirsch (Contributor)

2 Sep 2007

Activity: Talks and presentationsTalk or oral contributionOther


Chronic resveratrol induces a redox- dependent senescent-like growth arrest - role of the S-phase arrest

Verena Dirsch (Contributor)

13 Mar 2007

Activity: Talks and presentationsTalk or oral contributionOther


Effects of indirubin-3`-monoxime on platelet-derived growth factor signaling

Verena Dirsch (Contributor)

6 Sep 2006

Activity: Talks and presentationsTalk or oral contributionOther


Natural products: small molecule tools to probe for pharmacological targets?

Verena Dirsch (Contributor)

18 Nov 2005

Activity: Talks and presentationsTalk or oral contributionOther


Rotwein - die angenehme Art dem Herzinfarkt vorzubeugen ?

Verena Dirsch (Speaker)

18 Oct 2005

Activity: Talks and presentationsTalk or oral contributionOther


Naturstoffe - nicht nur ideal zur Wirkstoff- sondern auch zur Targetsuche?

Verena Dirsch (Contributor)

20 Jun 2005

Activity: Talks and presentationsTalk or oral contributionOther


Mit einem Naturstoff auf Target-Suche: Shp2, ein Hemmer vaskulärer Hypertrophie?

Verena Dirsch (Contributor)

28 Jan 2005

Activity: Talks and presentationsTalk or oral contributionOther


Rotweinpolyphenole - die angenehme Art dem Herzinfarkt vorzubeugen?

Verena Dirsch (Contributor)

26 Oct 2004

Activity: Talks and presentationsTalk or oral contributionOther


Resveratrol hemmt die Angiotensin II-induzierte Hypertrophie in vaskulären glatten Muskelzellen - aber über welches Target?

Verena Dirsch (Contributor)

28 Jun 2004

Activity: Talks and presentationsTalk or oral contributionOther


Polyphenole aus dem Rotwein - eine Erklärung für das "French Paradox"?

Verena Dirsch (Contributor)

25 May 2004

Activity: Talks and presentationsTalk or oral contributionOther


Mittels Resveratrol von der Angiotensin II-induzierten Hypertrophie zur Phosphatase Shp2

Verena Dirsch (Contributor)

24 May 2004

Activity: Talks and presentationsTalk or oral contributionOther


Resveratrol: Einfluss auf Proliferation/Zellzyklus und die Angiotensin II-induzierte Hypertrophy von vaskulären glatten Muskelzellen.

Verena Dirsch (Contributor)

21 Apr 2004

Activity: Talks and presentationsTalk or oral contributionOther


NO French Paradox without red wine polyphenols?

Verena Dirsch (Contributor)

31 Mar 2004

Activity: Talks and presentationsTalk or oral contributionOther


Naturstoffe als Tools?: was uns Resveratrol über das Angiotensin II Signaling in vaskulären glatten Muskelzellen erzählt......

Verena Dirsch (Contributor)

28 Jan 2004

Activity: Talks and presentationsTalk or oral contributionOther


Resveratrol and other cardiovascular active natural products.

Verena Dirsch (Contributor)

19 Jun 2003

Activity: Talks and presentationsTalk or oral contributionOther


Resveratrol: Einfluss auf Proliferation und Zellzyklus von vaskulären glatten Muskelzellen

Verena Dirsch (Contributor)

4 Jun 2003

Activity: Talks and presentationsTalk or oral contributionOther


Resveratrol: Mechanismen der Wachstumshemmung von vaskulären glatten Muskelzellen

Verena Dirsch (Contributor)

28 Apr 2003

Activity: Talks and presentationsTalk or oral contributionOther


Mechanism of vascular smooth muscle cell growth arrest by resveratrol

Verena Dirsch (Contributor)

22 Apr 2003

Activity: Talks and presentationsTalk or oral contributionOther


Einfluss von Resveratrol auf Zellzyklus und Proliferation von vaskulären glatten Muskelzellen

Verena Dirsch (Contributor)

9 Apr 2003

Activity: Talks and presentationsTalk or oral contributionOther


Resveratrol: Mechanismen der Wachstumshemmung von glatten Muskelzellen

Verena Dirsch (Contributor)

16 Dec 2002

Activity: Talks and presentationsTalk or oral contributionOther


Vasoprotective compounds made by nature?

Verena Dirsch (Contributor)

27 Jun 2002

Activity: Talks and presentationsTalk or oral contributionOther



Resveratrol, eine vielversprechende Substanz zur Prävention von Atherosklerose?

Verena Dirsch (Contributor)

10 Dec 2001

Activity: Talks and presentationsTalk or oral contributionOther


Cell-based techniques for the discovery and characterisation of anti-inflammatory natural products

Verena Dirsch (Invited speaker)

8 Oct 2001

Activity: Talks and presentationsTalk or oral contributionOther


Das Triterpen-Chinonmethid Pristimerin hemmt die Induktion der induzierbaren NO-Synthase in LPS-aktivierten RAW 264.7 Makrophagen

Verena Dirsch (Invited speaker)

2 Dec 1998

Activity: Talks and presentationsTalk or oral contributionOther


Der Einfluß von Allicin und Ajoen. zwei Verbindungen aus dem Knoblauch, auf die induzierbare NO-Synthase

Verena Dirsch (Speaker)

8 May 1998

Activity: Talks and presentationsTalk or oral contributionOther


Der RXR-Ligand LRK071 - Mechanismus und Funktion

Dirsch, V.

1/01/2231/12/25

Project: Research funding


TMC-VASC

Dirsch, V.

1/07/1230/06/14

Project: Research funding


Good practice in TCM

Dirsch, V., Kopp, B. & Szabo, A.

1/05/0931/10/12

Project: Research funding


Drugs from Nature Targeting Inflammation

Kopp, B. & Dirsch, V.

1/04/0831/03/11

Project: Research funding


Resveratrol

Dirsch, V.

1/07/0630/06/09

Project: Research funding


Protein Kinase Research

Dirsch, V.

1/03/0628/02/09

Project: Research funding


Department of Pharmaceutical Sciences

Deputy Head

Josef-Holaubek-Platz 2 (UZA II)
1090 Wien
Room: 2G452

T: +43-1-4277-55270

verena.dirsch@univie.ac.at