Consultation hours: Wed 14:00 - 15:00, 2E405 or online, registration per E-mail at latest till Friday the week before
AI in Drug Discovery and Toxicity Prediction
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
In silico MIE Prediction
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Prediction of Toxicity
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Prediction of Toxicity - let's use Fingerprints
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
In silica prediction of toxicity - from QSAR models to biological fingerprinting
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Predicting chemicals' Molecular Initiating Events (MIEs) based on protein structure
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Structure-based prediction of molecular initiating events - where are we?
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Transporter Informatics and Computational Toxicology - from QSAR to Machine Learning and beyond
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Wie lassen sich Elternschaft und Wissenschaft vereinbaren?
Wöhrer, V. (Speaker), Ecker, G. (Speaker), Garstenauer, T. (Speaker), Herr, B. (Speaker) & Leal, A. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Arzneistoffentwicklung in Zeiten personalisierter Medizin
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
In silico Toxicology - from prediction of transporter interaction profiles to toxicological read across and beyond
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
The OMICS approach - the buzz that makes the world go round
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Upsampling of Molecules to create datasets large enough for Deep learning in toxicity prediction
Hemmerich, J. (Speaker), Asilar, E. (Contributor) & Ecker, G. (Contributor)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
DEEPHUNT: HEPATOTOXICITY USING NEURAL NETWORKS.
Asilar, E. (Speaker), Hemmerich, J. (Contributor) & Ecker, G. (Contributor)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Exploring the use of neural networks for prediction of toxicities
Hemmerich, J. (Speaker), Asilar, E. (Contributor) & Ecker, G. (Contributor)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Predicting ligand residence time - it's all about how long you stay
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Leveraging integrated life science data – the power of workflows
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
In silico Toxicology - from prediction of transporter interaction profiles to toxicological read across and beyond
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Linking open data - from transporter interaction profiles to toxicity prediction
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Predicting drug residence time - its all about how long you stay
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Open PHACTS - Exploiting semantically integrated life science data for transporter profiling
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Leveraging linked open data - from transporter interaction profiling to toxicity prediction and beyond
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Innovative Medicines Initiative - From semantic data integration to risk assessment
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Leveraging open data for development of ABC-transporter inhibitors
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Leveraging linked open data - from transporter profiling to toxicity prediction and beyond
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Leveraging linked open data - from transporter interaction profiling to toxicity prediction and beyond
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Exploiting semantically integrated life science data - from transporter profiling to toxicity prediction
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
The power of open data - linking transporter interaction profiles to in vivo toxicity
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Leveraging linked open data - from transporter interaction profiles to toxicity prediction
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Open Innovation in the Age of Big Data
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Exploiting Linked Open Data - the Power of Workflows
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Quantitative structure-kinetics relationships - can we predict on and off-kinetics?
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
the Open PHACTS Discovery Platform - Semantic data integration in Pharmacoinformatics
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
It's all about integration - from docking to structure-based classification and prediction of side effects
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
The Open PHACTS Discovery Platform - Semantic data integration for medicinal chemists
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Open PHACTS - the use of open data for in silico models
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Exploiting integrated open data in drug discovery
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
It's all about integration - From docking poses to structure-based classification and prediction of side effects
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Open PHACTS - Building an open pharmacological space
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Experimental data guided docking for elucidating the molecular basis of drug-transporter interaction
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Experimental data guided docking allows to elucidate the molecular basis of drug-transporter interaction
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Arzneistoffdesign am computer - Spielerei oder Wissenschaft
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Computational Drug Design
Ecker, G. (Keynote speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Integrated approaches - from docking poses to prediction of side effects
Ecker, G. (Keynote speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Exploiting open data - a new era in pharmacoinformatics
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Open PHACTS - a novel platform for integrated data-driven drug discovery
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Arzneistoffentwicklung am Computer - Fact or Fiction?
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Pharmacoinformatics - from data integration to in silico screening
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
The medicinal chemistry of drug transport – knowledge based ligand design.
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Ligand efficiency and lipophilic efficiency – versatile parameters for the design of inhibitors of transmembrane transporters?
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
The molecular basis of drug-transporter interaction - science or fiction?
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Arzneistofftransporter und ihre Rolle in der Pharmaforschung
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Drug Transporters – Structure, Function, and Modulation
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Knowledge driven ligand design – ligand-based design meets protein structures
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Ligand- and structure-based approaches for targeting drug transporter
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Experimental data guided ligand docking - a versatile approach for elucidating the molecular basis of drug/transporter interactions
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Computational drug design - where are we and where to go
Ecker, G. (Keynote speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Prediction of ADMET – from rules to networks
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
The medicinal chemistry of drug transporters
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
In silico studies for prediction of substrates and inhibitors of P-glycoprotein.
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
The medicinal chemistry of P-glycoprotein – ligand- and target-based studies
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
In silico models for classification of ABC-transporter substrates to improve ADMET profiling
Ecker, G. (Contributor)
Activity: Talks and presentations › Talk or oral contribution › Other
Pharmacoinformatics – combining experimental pharmaceutical sciences with in silico methods
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Predicting substrate properties for ABC-Transporter - Safety Sciences on the molecular level
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
SIBAR descriptors and support vector machines for ABCB1 substrate prediction
Ecker, G. (Contributor)
Activity: Talks and presentations › Talk or oral contribution › Other
Predicting Ligands of ABC-transporter - a long way to go
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Predicting Interaction with ABC-Transporters involved in ADME
Ecker, G. (Keynote speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Safety Sciences in silico - Analyse unerwünschter Wirkungen durch molekulare Modellierung
Ecker, G. (Keynote speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Optimising ligands for promiscuous targets - a case study for P-glycoprotein inhibitors
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Prediction of ligands of promiscuous targets - safety sciences on the molecular level
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Optimizing Ligands for Promiscuous Targets - A Case Study for P-glycoprotein Inhibitors
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Pharmacoinformatic approaches to target polyspecific proteins
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Use your brain - artificial neural networks in drug discovery
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
EUROPIN - A European Pharmacoinformatics Initative
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
P-glycoprotein - from inhibitor design to substrate prediction
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Prediction of substrate properties for ABC Drug-Transporter: The challenge continues
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Classification models for hERG inhibitors by counter-propagation neural networks
Ecker, G. (Contributor)
Activity: Talks and presentations › Talk or oral contribution › Other
Pharmacoinformatic approaches to target P-glycoprotein - from inhibitor design to substrate prediction
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
EUROPIN - A European Pharmacoinformatics Initative
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Predicting ligands for P-glycoprotein - safety sciences on the molecular level
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Computermodels for predicting P-glycoprotein substrates - can we guide the lead optimisation process?
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Linking chemical space to biological space - challenges for high-throughput computing
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Use your brain - artificial neural networks in drug design
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Polyspecific proteins - safety sciences on the molecular level
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
P-glycoprotein - design of inhibitors and prediction of substrates
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Vortrag auf Kongress: Recent developments in physics of fundamental interactions
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Multispecificity of drug transporter - probing inhibitor selectivity for the human drug efflux transporter ABCB1 and ABCG2
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Chemigenomics and Drug Discovery
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
P-glycoprotein - from target to antitarget
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Predicting ligands for ABC-transporter - structure-based vs ligand-based approaches
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Polyspecific proteins - a challenge in pharmacoinformatics
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Comparative Analysis of two Different Classifiers for Predicting P-glycoprotein Substrates
Ecker, G. (Contributor)
Activity: Talks and presentations › Talk or oral contribution › Other
Machine learning methods for classification and hit identification
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Role of structural models of P-glycoprotein - the prediction of actively transported small molecules
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Von Penicillin bis Viagra : Arzneistoffentwicklung gestern - heute - morgen
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Von Penicillin bis Viagra : Arzneistoffentwicklung gestern - heute - morgen
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
In silico methods for hit identification and prediction of biological activities
Ecker, G. (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Drug efflux pumps - From target to antitarget
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
MDR - Multiple Drug Resistance
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Pharmacoinformatic approaches to target the molecular basis of polyspecificity
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
ABC-transporter as antitargets
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
In silico methods for prediction of P-glycoprotein substrates
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Non-linear methods and machine learning in drug discovery
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
In vitro and in silico models for prediction of P-glycoprotein substrates
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
A flow based hollow-fiber blood-brain barrier in vitro model with immortalised cell line PBMEC/C1-2
Ecker, G. (Contributor)
Activity: Talks and presentations › Talk or oral contribution › Other
P-glycoprotein - From target to antitarget
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Pharmacoinformatic approaches to target polyspecific proteins
Ecker, G. (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Add medical genetic solutions to RESOLUTE
Ecker, G. (Project Lead), Dangl, A. (Admin), Colas, C. (Scientific Project Staff), Huang, J. (Scientific Project Staff), Digles, D. (Scientific Project Staff) & Schwarzenböck, M. (Admin)
1/06/21 → 31/05/23
Project: Research funding
RISK-HUNT3R: RISK assessment of chemicals integrating HUman centric Next generation Testing strategies promoting the 3Rs
Ecker, G. (Project Lead), Dangl, A. (Admin) & Schwarzenböck, M. (Project Staff)
1/06/21 → 31/05/26
Project: Research funding
ReSOLUTE: Research Empowerment on Solute Carriers
Ecker, G. (Project Lead), Dangl, A. (Admin), Digles, D. (Scientific Project Staff), Colas, C. (Scientific Project Staff) & Schwarzenböck, M. (Project Staff)
1/07/18 → 31/12/23
Project: Research funding
eTRANSAFE: Enhancing TRANslational SAFEty Assessment through Integrative Knowledge Management
Ecker, G. (Project Lead), Dangl, A. (Admin), Hemmerich, J. (Scientific Project Staff), Smajic, A. (Scientific Project Staff), Grandits, M. (Scientific Project Staff), Kaiser, F. (Scientific Project Staff) & Schwarzenböck, M. (Project Staff)
1/09/17 → 28/02/23
Project: Research funding
FAIRness for Life Science Data in Austria
Ecker, G. (Project Lead)
1/06/17 → 31/12/19
Project: Research funding
TransQST: Translational quantitative systems toxicology to improve the understanding of the safety of medicines
Ecker, G. (Project Lead), Grandits, M. (Admin), Dangl, A. (Admin), Füzi, B. (Scientific Project Staff) & Schwarzenböck, M. (Project Staff)
1/01/17 → 30/06/22
Project: Research funding
EU-ToxRisk: EU-ToxRisk
Ecker, G. (Project Lead), Grandits, M. (Scientific Project Staff), Dangl, A. (Admin), Zdrazil, B. (Scientific Project Staff), Jain, S. (Scientific Project Staff) & Schwarzenböck, M. (Project Staff)
1/01/16 → 31/12/21
Project: Research funding
K4DD
Ecker, G. (Project Lead), Grandits, M. (Co-Lead) & Dangl, A. (Admin)
1/11/12 → 31/10/17
Project: Research funding
Molecular Drug Targets
Hering, S. (Project Lead), Ecker, G. (Co-Lead), Maulide, N. (Co-Lead), Weinzinger, A. (Co-Lead) & Gonzalez Herrero, L. (Co-Lead)
1/12/10 → 31/12/22
Project: Research funding
Department of Pharmaceutical Sciences
Josef-Holaubek-Platz 2 (UZA II)
1090 Wien
Room: 2E405
T: +43-1-4277-55110