Assoz. Prof. Dipl.-Biochem. Dr. Elke Heiß, Privatdoz.
T: +43-1-4277-55993
1 - 20 out of 147
Braunböck-Müller B, Heiß E. Impact of cell culture conditions on NRF2 (nuclear factor E2 p45-related factor 2)-driven reporter gene expression. Advances in Redox Research. 2025 Sept;16:100136. Epub 2025 Jun 9. doi: 10.1016/j.arres.2025.100136

Petsouki E, Gerakopoulos V, Gianniou DD, Heiß E, Trougakos IP. Involvement of NRF2 and AMPK signaling in aging and progeria: a digest. Redox biology. 2025 Sept;85:103782. Epub 2025 Jul 21. doi: 10.1016/j.redox.2025.103782

Korczak M, Redl M, Roszkowski P, Granica S, Rollinger JM, Heiss E et al. Synthesis, characterization, and anti-inflammatory potential of serotonin- and dopamine-conjugates of urolithin A. Biomedicine & Pharmacotherapy. 2025 Aug;189:118282. Epub 2025 Jun 18. doi: 10.1016/j.biopha.2025.118282


Cannavacciuolo C, Napolitano A, Dirsch VM, Heiss EH, Masullo M, Piacente S. Oleraceins from Portulaca oleracea leaves: Quali-quantitative determination and antioxidant potential. Current Research in Food Science. 2025 Jan 30;10:100992. Epub 2025 Jan 30. doi: 10.1016/j.crfs.2025.100992

Li W, Cai Z, Schindler F, Afjehi-Sadat L, Montsch B, Heffeter P et al. Elevated PINK1/Parkin-Dependent Mitophagy and Boosted Mitochondrial Function Mediate Protection of HepG2 Cells from Excess Palmitic Acid by Hesperetin. Journal of Agricultural and Food Chemistry. 2024 Jun 12;72(23):13039-13053. Epub 2024 May 29. doi: 10.1021/acs.jafc.3c09132

Bahiraii S, Braunböck-Müller B, Heiss EH. Increased Glycolytic Activity Is Part of Impeded M1(LPS) Macrophage Polarization in the Presence of Urolithin A #. Planta Medica. 2024 Jun 6;90(7-8):546-553. doi: 10.1055/a-2240-7462

Heiß E, (ed.), Rollinger JM, (ed.). Special Issue Celebrating the Austrian Pharmacognosy. Planta Medica: natural products and medicinal plant research. 2024 Jun 6;90(Special Issue):496-497. doi: 10.1055/a-2285-6455

Cai Z, Li W, Hager S, Wilson JL, Afjehi-Sadat L, Heiss EH et al. Targeting PHGDH reverses the immunosuppressive phenotype of tumor-associated macrophages through α-ketoglutarate and mTORC1 signaling. Cellular and Molecular Immunology. 2024 May;21(5):448-465. Epub 2024 Feb. doi: 10.1038/s41423-024-01134-0


Bahiraii S, Brenner M, Weckwerth W, Heiss EH. Sulforaphane impedes mitochondrial reprogramming and histone acetylation in polarizing M1 (LPS) macrophages. Free Radical Biology and Medicine. 2024 Mar;213:443-456. doi: 10.1016/j.freeradbiomed.2024.01.029

Rollinger JM, Heiß E. Special Issue Celebrating the Austrian Pharmacognosy. Planta Medica: natural products and medicinal plant research. 2024;90(07/08):496-497. doi: 10.1055/a-2285-6455

Petsouki E, Ender S, Sosa Cabrera SN, Heiss EH. AMPK-Mediated Phosphorylation of Nrf2 at S374/S408/S433 Favors Its βTrCP2-Mediated Degradation in KEAP1-Deficient Cells. Antioxidants. 2023 Aug;12(8):1586. doi: 10.3390/antiox12081586


Blažević T, Ciotu CI, Gold-Binder M, Heiss EH, Fischer MJM, Dirsch VM. Cultured rat aortic vascular smooth muscle cells do not express a functional TRPV1. PLoS ONE. 2023 Feb;18(2):e0281191. doi: 10.1371/journal.pone.0281191

Li W, Cai Z, Schindler F, Bahiraii S, Brenner M, Heiss EH et al. Norbergenin prevents LPS-induced inflammatory responses in macrophages through inhibiting NFκB, MAPK and STAT3 activation and blocking metabolic reprogramming. Frontiers in Immunology. 2023;14:1-20. 1117638. doi: 10.3389/fimmu.2023.1117638

Cai Z, Li W, Brenner M, Bahiraii S, Heiss EH, Weckwerth W. Branched-chain ketoacids derived from cancer cells modulate macrophage polarization and metabolic reprogramming. Frontiers in Immunology. 2022 Oct 13;13:966158. doi: 10.3389/fimmu.2022.966158

Boakye YD, Osafo N, Oppong-Kyekyeku J, Abotsi WKM, Boakye-Gyasi E, Heiss E et al. Regulation of Nrf2 and NF-κB activities may contribute to the anti-inflammatory mechanism of xylopic acid. Inflammopharmacology : experimental and therapeutic studies. 2022 Oct;30(5):1835-1841. doi: 10.1007/s10787-022-00950-y

Cannavacciuolo C, Napolitano A, Heiss EH, Dirsch VM, Piacente S. Portulaca oleracea, a rich source of polar lipids: Chemical profile by LC-ESI/LTQOrbitrap/MS/MSn and in vitro preliminary anti-inflammatory activity. Food Chemistry. 2022 Sept 15;388:132968. doi: 10.1016/j.foodchem.2022.132968

Petsouki E, Cabrera SNS, Heiss EH. AMPK and NRF2: Interactive players in the same team for cellular homeostasis? Free Radical Biology & Medicine. 2022 Sept;190:75-93. doi: 10.1016/j.freeradbiomed.2022.07.014

1 - 20 out of 147

NRF2 in diologue with AMP-activated kinase and cellular energy metabolism

Heiß, E. (Speaker)

6 Jun 2025

Activity: Talks and presentationsTalk or oral contributionScience to Science


Immunometabolic responses of macrophages to Nrf2 activation

Heiß, E. (Speaker)

5 Mar 2025

Activity: Talks and presentationsTalk or oral contributionScience to Science


Nrf2 at the crossroad of cellular energy metabolism and stress response

Heiß, E. (Speaker)

20 Feb 2025

Activity: Talks and presentationsTalk or oral contributionScience to Science


Natural products at the interface between cellular energy metabolism and stress response

Heiß, E. (Speaker)

31 Oct 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


NRF2, natural products and type 2 diabetes- a clar cut picture?

Heiß, E. (Speaker)

27 Jun 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


NRF2- Driver and Passenger of Cellular Metabolism

Heiß, E. (Speaker)

26 Jun 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


Immunometabolic Responses Elicited by Sulforaphane in murine M1 (LPS) polarizing macrophages

Heiß, E. (Speaker)

19 Apr 2024

Activity: Talks and presentationsTalk or oral contributionScience to Science


In silico and in vitro Approach to Assess Direct Allosteric AMPK Activators from Nature

Kirchweger, B. (Speaker), Wasilewicz, A. (Contributor), Fischhuber, K. (Contributor), Tahir, A. (Contributor), Chen, Y. (Contributor), Heiß, E. (Contributor), Langer, T. (Contributor), Kirchmair, J. (Contributor) & Rollinger, J. M. (Contributor)

20 May 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


AMP(K)lifying the Nrf2 dependent stress response

Heiß, E. (Speaker)

10 Jan 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


AMP(K)lifying Nrf2: : The crosstalk between Nrf2 and the metabolic regulator AMPK

Heiß, E. (Speaker)

2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


Natural products at the interface of cellular metabolism and stress response

Heiß, E. (Speaker)

7 Sept 2021

Activity: Talks and presentationsTalk or oral contributionScience to Science


Identification of AMPK-dependent phosphorylation sites in the transcription factor Nrf2 and their functional relevance in cells

Matzinger, M. (Speaker), Fischhuber, K. (Contributor), Mechtler, K. (Contributor) & Heiß, E. (Contributor)

30 Sept 20184 Oct 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Combinatory effects of glutathione-modulation on the toxicity of deoxynivalenol (DON) and NX-3 and its co-regulated metabolite butenolide (BUT)

Wölflingseder, L. (Keynote speaker), Del Favero, G. (Contributor), Heiß, E. (Contributor), Adam, G. (Contributor) & Marko, D. (Contributor)

11 Jun 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Natural products at the interface of cellular metabolism and phenotypic response

Heiß, E. (Speaker)

2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


: Bioactivity screening for xylopic acid as well as geraniin and its gut metabolites in cell-based assays

Heiß, E. (Speaker)

2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


Molekulare Mechanismen von Naturprodukten- Forschungsspielerei oder Praxisrelevanz?

Heiß, E. (Speaker)

26 Oct 2016

Activity: Talks and presentationsTalk or oral contributionScience to Public


Dissecting the molecular mechanism of bioactive natural products

Heiß, E. (Speaker)

16 Dec 2015

Activity: Talks and presentationsTalk or oral contributionOther


Polypharmacology of Natural Products- Friend or Foe ?

Heiß, E. (Speaker)

5 Dec 2015

Activity: Talks and presentationsTalk or oral contributionOther


Using xanthohumol to reveal an AMPK-mediated boost of Nrf2 signaling

Heiß, E. (Speaker)

24 Aug 2015

Activity: Talks and presentationsTalk or oral contributionOther


Dissecting the molecular mechanism of bioactive natural products

Heiß, E. (Speaker)

23 Aug 2015

Activity: Talks and presentationsTalk or oral contributionOther


AMP-activated kinase boosts Nrf2 signaling

Heiß, E. (Speaker)

7 Jan 2015

Activity: Talks and presentationsTalk or oral contributionOther


Bioactive Natural Products in Cell Biology -a story of tools, targets and hits-

Heiß, E. (Speaker)

Nov 2014

Activity: Talks and presentationsTalk or oral contributionOther


Targets, Tools and Leads- the potential of natural products

Heiß, E. (Speaker)

Jan 2014

Activity: Talks and presentationsTalk or oral contributionOther


Alleviation of vascular and metabolic dysfunction by bioactive natural products

Heiß, E. (Speaker)

2014

Activity: Talks and presentationsTalk or oral contributionOther


The Potential of Natural Products in the Discovery Novel Targets, Leads and Tools

Heiß, E. (Speaker)

Jun 2013

Activity: Talks and presentationsTalk or oral contributionOther


Natural Products as Tools to Understand and Modulate Cellular Signaling Processes

Heiß, E. (Speaker)

May 2013

Activity: Talks and presentationsTalk or oral contributionOther


TARGETS, TOOLS & LEADS The different exits for natural products on the road of in vitro pharmacology

Heiß, E. (Contributor)

25 Oct 2012

Activity: Talks and presentationsTalk or oral contributionOther


Is there dual protection from hyperglycemia and endothelial dysfunction by activated Nrf2 ?

Heiß, E. (Selected presenter)

1 Dec 2011

Activity: Talks and presentationsTalk or oral contributionOther



Natural products to combat cardiovascular and metabolic disease- screening and molecular mechanisms

Heiß, E. (Invited speaker)

2 Mar 2010

Activity: Talks and presentationsTalk or oral contributionOther


Virtual and real screening of natural products to find effective modulators of protein tyrosine phosphatase PTP1B.

Heiß, E. (Contributor)

18 Apr 2009

Activity: Talks and presentationsTalk or oral contributionOther


Selective inhibition of platelet-derived growth factor-induced signalling cascades by indirubin-3'-monoxime

Heiß, E. (Contributor)

2 Sept 2007

Activity: Talks and presentationsTalk or oral contributionOther


Chronic resveratrol induces a redox- dependent senescent-like growth arrest - role of the S-phase arrest

Heiß, E. (Speaker)

13 Mar 2007

Activity: Talks and presentationsTalk or oral contributionOther


Effects of indirubin-3`-monoxime on platelet-derived growth factor signaling

Heiß, E. (Contributor)

6 Sept 2006

Activity: Talks and presentationsTalk or oral contributionOther


AMP(K)lifying Nrf2 target gene expression

Heiß, E. (Project Lead), Weckwerth, W. (Co-Lead), Matzinger, M. (Project Staff) & Fischhuber, K. (Project Staff)

4/01/213/07/24

Project: Research funding


"Metabolic immunomodulation" by natural products

Heiß, E. (Project Lead)

1/10/1931/03/23

Project: Research funding


Role of AMPK for the Nrf2-dependent cellular stress response

Heiß, E. (Project Lead)

3/10/162/07/20

Project: Research funding


antiprol.Aktivität v.I3MC

Heiß, E. (Project Lead)

1/12/1030/11/13

Project: Research funding


Department of Pharmaceutical Sciences

Josef-Holaubek-Platz 2 (UZA II)
1090 Wien
Room: 2F463

T: +43-1-4277-55993

elke.heiss@univie.ac.at