Lächelt U. RNA pharmaceutics: Formulation technology, biophysics and kinetics. European Journal of Pharmaceutics and Biopharmaceutics. 2025 May;210:114683. doi: 10.1016/j.ejpb.2025.114683

Yazdi M, Burghardt T, Seidl J, Lächelt U, Wagner E. Evolution of Lipo-Xenopeptide Carriers for siRNA Delivery: Interplay of Stabilizing Subunits. Bioconjugate Chemistry. 2025 Apr 16;36(4):846-858. doi: 10.1021/acs.bioconjchem.5c00096

Weiss S, Decker S, Kugler C, Gómez LB, Fasching H, Benisch D et al. Accelerated Endosomal Escape of Splice-Switching Oligonucleotides Enables Efficient Hepatic Splice Correction. ACS applied materials & interfaces. 2025 Feb 12;17(6):9000-9018. Epub 2025 Jan 28. doi: 10.1021/acsami.4c19340

Luo X, Germer J, Burghardt T, Grau M, Lin Y, Höhn M et al. Dual pH-responsive CRISPR/Cas9 ribonucleoprotein xenopeptide complexes for genome editing. European Journal of Pharmaceutical Sciences. 2025 Feb 1;205:106983. 106983. Epub 2024 Dec 6. doi: 10.1016/j.ejps.2024.106983

Zhu X, Shi Z, Mao Y, Lächelt U, Huang R. Cell Membrane Perforation: Patterns, Mechanisms and Functions. Small. 2024 Jun 12;20(24):2310605. Epub 2024. doi: 10.1002/smll.202310605

Germer J, Lessl AL, Pöhmerer J, Grau M, Weidinger E, Höhn M et al. Lipo-Xenopeptide Polyplexes for CRISPR/Cas9 based Gene editing at ultra-low dose. Journal of Controlled Release. 2024 Jun;370:239-255. Epub 2024 Apr 27. doi: 10.1016/j.jconrel.2024.04.037

Zhou F, Huang L, Li S, Yang W, Chen F, Cai Z et al. From structural design to delivery: mRNA therapeutics for cancer immunotherapy. Exploration. 2024 Apr;4(2):20210146. doi: 10.1002/EXP.20210146

Berger S, Lächelt U, Wagner E. Dynamic carriers for therapeutic RNA delivery. Proceedings of the National Academy of Sciences of the United States of America. 2024 Mar 12;121(11):e2307799120. doi: 10.1073/pnas.2307799120

Albuquerque LJC, de Oliveira FA, Christoffolete MA, Nascimento-Sales M, Berger S, Wagner E et al. Nucleic acid delivery to retinal cells using lipopeptides as a potential tool towards ocular gene therapies. Journal of Colloid and Interface Science. 2024 Feb;655:346-356. doi: 10.1016/j.jcis.2023.11.003

Lyu M, Yazdi M, Lin Y, Höhn M, Lächelt U, Wagner E. Receptor-Targeted Dual pH-Triggered Intracellular Protein Transfer. ACS Biomaterials Science & Engineering. 2024 Jan 8;10(1):99-114. Epub 2022 Jul 8. doi: 10.1021/acsbiomaterials.2c00476

Lessl AL, Pöhmerer J, Lin Y, Wilk U, Höhn M, Hörterer E et al. mCherry on Top: A Positive Read-Out Cellular Platform for Screening DMD Exon Skipping Xenopeptide-PMO Conjugates. Bioconjugate Chemistry. 2023 Dec 20;34(12):2263-2274. Epub 2023 Nov 22. doi: 10.1021/acs.bioconjchem.3c00408

Öztürk Ö, Lessl AL, Höhn M, Wuttke S, Nielsen PE, Wagner E et al. Peptide nucleic acid-zirconium coordination nanoparticles. Scientific Reports. 2023 Dec;13(1):14222. doi: 10.1038/s41598-023-40916-w

Liu Z, Zimpel A, Lächelt U, Pozzi M, Gonzalez MG, Chakraborty I et al. Uptake and Intracellular Fate of Fluorophore Labeled Metal–Organic-Framework (MOF) Nanoparticles: Environment & Health. Environment & Health. 2023 Oct 20;1(4):270-277. doi: 10.1021/envhealth.3c00075

Hall A, Bartek J, Wagner E, Lächelt U, Moghimi SM. High-resolution bioenergetics correlates the length of continuous protonatable diaminoethane motif of four-armed oligo(ethanamino)amide transfectants to cytotoxicity. Journal of Controlled Release. 2023 Aug 4;361:115-129. doi: 10.1016/j.jconrel.2023.07.051

Lin Y, Luo X, Burghardt T, Dorrer S, Höhn M, Wagner E et al. Chemical Evolution of Amphiphilic Xenopeptides for Potentiated Cas9 Ribonucleoprotein Delivery. Journal of the American Chemical Society. 2023 Jul 19;145(28):15171-15179. doi: 10.1021/jacs.3c01902

Shen F, Lin Y, Höhn M, Luo X, Döblinger M, Wagner E et al. Iron-Gallic Acid Peptide Nanoparticles as a Versatile Platform for Cellular Delivery with Synergistic ROS Enhancement Effect. Pharmaceutics. 2023 Jul;15(7):1789. doi: 10.3390/pharmaceutics15071789

Qin Y, Zhang X, Lächelt U, Huang R. Unveiling the Multiple Tumor-Targeted Impairments of Covalent-Organic Framework-Switched Photothermal Shielding Nanoparticles. Advanced Functional Materials. 2023 Mar 2;33(10):2211075. Epub 2022. doi: 10.1002/adfm.202211075

Lin Y, Wilk U, Pöhmerer J, Hörterer E, Höhn M, Luo X et al. Folate Receptor-Mediated Delivery of Cas9 RNP for Enhanced Immune Checkpoint Disruption in Cancer Cells. Small. 2023 Jan 11;19(2):e2205318. Epub 2022 Nov 18. doi: 10.1002/smll.202205318

Mirzazadeh Dizaji N, Lin Y, Bein T, Wagner E, Wuttke S, Lächelt U et al. Biomimetic Mineralization of Iron-Fumarate Nanoparticles for Protective Encapsulation and Intracellular Delivery of Proteins. Chemistry of Materials. 2022 Oct 11;34(19):8684-8693. doi: 10.1021/acs.chemmater.2c01736