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Ass.-Prof. Dipl.-Ing. Karin Ortmayr, PhD
Karin Ortmayr
T: +43-1-4277-55273
https://pharmakognosie.univie.ac.at/people/ortmayr-karin/
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Ortmayr K, Zampieri M. Sorting‐free metabolic profiling uncovers the vulnerability of fatty acid β‐oxidation in in vitro quiescence models. Molecular Systems Biology. 2022 Sep;18(9):e10716. doi: 10.15252/msb.202110716
Ortmayr K, Moreno RDLC, Zampieri M. Expanding the search for small-molecule antibacterials by multidimensional profiling. Nature Chemical Biology. 2022 Jun;18(6):584-595. doi: 10.1038/s41589-022-01040-4
Anglada-Girotto M, Handschin G, Ortmayr K, Campos AI, Gillet L, Manfredi P et al. Combining CRISPRi and metabolomics for functional annotation of compound libraries. Nature Chemical Biology. 2022 May;18(5):482-491. doi: 10.1038/s41589-022-00970-3
Ortmayr K, Dubuis S, Zampieri M. Metabolic profiling of cancer cells reveals genome-wide crosstalk between transcriptional regulators and metabolism. Nature Communications. 2019 Apr 23;10(1):1841. doi: 10.1038/s41467-019-09695-9
Ortmayr K, Dubuis S, Zampieri M. A framework for large-scale metabolome drug profiling links coenzyme A metabolism to the toxicity of anti-cancer drug dichloroacetate. Communications Biology. 2018 Aug 3;1(1):101. doi: 10.1038/s42003-018-0111-x
Ortmayr K, Charwat V, Kasper C, Hann S, Koellensperger G. Uncertainty budgeting in fold change determination and implications for non-targeted metabolomics studies in model systems. The Analyst. 2017 Jan 1;142(1):80-90. doi: 10.1039/c6an01342b
Ortmayr K, Causon TJ, Hann S, Koellensperger G. Increasing selectivity and coverage in LC-MS based metabolome analysis. Trends in Analytical Chemistry. 2016 Sep;82:358-366. doi: 10.1016/j.trac.2016.06.011
Ortmayr K, Schwaiger M, Drexler H, Mairinger T, Causon T, Hann S et al. Metabolomics trifft Methodenvalidierung - Analytische Herausforderungen in der modernen ungezielten Metabolomanalyse mittels LC-MS. In Book of Abstracts. 2016
Megson ZA, Pittenauer E, Duda KA, Engel R, Ortmayr K, Koellensperger G et al. Inositol-phosphodihydroceramides in the periodontal pathogen Tannerella forsythia: Structural analysis and incorporation of exogenous myo-inositol. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 2015 Nov;1851(11):1417-1427. doi: 10.1016/j.bbalip.2015.08.004
Hermann G, Rampler E, Ortmayr K, Schwaiger M, Neubauer S, Chu DB et al. The assisting role of elemental speciation analysis in metabolomics and proteomics. In Book of Abstracts. 2015
Ortmayr K, Schwaiger M, Drexler H, Mairinger T, Hermann G, Causon T et al. Towards validating LC-MS based metabolomics – overcoming analytical challenges with chromatographic enhancements and normalization strategies. In Book of Abstracts. 2015
Ortmayr K, Hann S, Köllensperger G. Towards validating LC-MS based metabolomics – chromatographic enhancements and normalization strategies. In Rainer M, editor, Book of Abstracts. 2015
Mairinger T, Drexler H, Chu DB, Neubauer S, Troyer C, Ortmayr K et al. Measurement uncertainty of isotopologue fractions determined via mass spectrometry for metabolic flux analysis. In Samuel L, editor, Book of Abstracts. 2015
Ortmayr K, Hann S, Köllensperger G. Complementing reversed phase selectivity with porous graphitized carbon to increase the metabolome coverage in an on-line two-dimensional LC-MS setup for metabolomics. In Gössler W, Leitner E, Wiltsche H, editors, Book of Abstracts. 2015
Hermann G, Neubauer S, Chu DB, Ortmayr K, Hann S, Köllensperger G. Elemental speciation analysis - current developments and future perspectives. In Gössler W, Leitner E, Wiltsche H, editors, Book of Abstracts. 2015
Mairinger T, Drexler H, Chu DB, Neubauer S, Troyer C, Ortmayr K et al.. Neue massenspektrometrische Analysenstrategien für Fluxomics und Metabolomics in der industriellen Biotechnologie. 2015. Paper presented at 32. Forum Analytik Wien, Wien, Austria.
Köllensperger G, Hermann G, Ortmayr K, Hann S. Sulfur speciation analysis in biotechnology. In Karst U, Sperling M, Vogel M, editors, Book of Abstracts. 2015
Ortmayr K, Schwaiger M, Hann S, Koellensperger G. An integrated metabolomics workflow for the quantification of sulfur pathway intermediates employing thiol protection with N-ethyl maleimide and hydrophilic interaction liquid chromatography tandem mass spectrometry. The Analyst. 2015;140(22):7687-7695. doi: 10.1039/c5an01629k
Ortmayr K, Hann S, Koellensperger G. Complementing reversed-phase selectivity with porous graphitized carbon to increase the metabolome coverage in an on-line two-dimensional LC-MS setup for metabolomics. The Analyst. 2015;140(10):3465-3473. doi: 10.1039/c5an00206k
Hann S, Mairinger T, Binh CD, Neubauer S, Ortmayr K, Köllensperger G. GC-qTOFMS for determination of accurate isotopologue ratios and tandem mass isotopomer ratios for metabolic flux analysis of the central carbon metabolism. In Zenobi R, editor, Book of Abstracts . 2014
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Department of Pharmaceutical Sciences

Josef-Holaubek-Platz 2 (UZA II)
1090 Wien
Room: 2G154

T: +43-1-4277-55273

karin.ortmayr@univie.ac.at