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Assoz. Prof. Dipl.-Ing. Dr. Julien Orts, M.Sc. PhD
T: +43-1-4277-55001
1 - 20 out of 52
Yan X, Jia X, Luo Z, Ji S, Zhang MJ, Zhang H et al. An enzymatic dual-oxa Diels–Alder reaction constructs the oxygen-bridged tricyclic acetal unit of (–)-anthrabenzoxocinone. Nature Chemistry. 2025 Jul;17(7):1058-1066. doi: 10.1038/s41557-025-01804-0
Mares J, Tarang GS, Marin D, Mobli M, Redon S, Orts J. Streamlined Postprocessing of NMR Structures with the Molecular Restrainer: A Universal Tool for High-Quality Protein–Ligand Models and Non-Standard Amino Acid Residues. International Journal of Molecular Sciences. 2025 May 26;26(11):5091. 5091. doi: 10.3390/ijms26115091
Bütikofer M, Torres F, Kadavath H, Gämperli N, Abi Saad MJ, Zindel D et al. NMR2-Based Drug Discovery Pipeline Presented on the Oncogenic Protein KRAS. Journal of the American Chemical Society. 2025 Apr 23;147(16):13200-13209. doi: 10.1021/jacs.4c16762
Orts J. Swiss Science Concentrates. Chimia. 2025. doi: 10.2533/chimia.2025.571
Altincekic N, Jores N, Löhr F, Richter C, Ehrhardt C, Blommers MJJ et al. Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies. ACS Chemical Biology. 2024 Feb 16;19(2):563-574. Epub 2024 Jan 17. doi: 10.1021/acschembio.3c00720
Buetikofer M, Orts J. NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with 1-(5-methoxy-1H-indol-3-yl)-N,N-dimethylmethanamine. 2024. doi: 10.2210/pdb8qe6/pdb
Buetikofer M, Orts J. NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with (2E)-3-(1H-indol-2-yl)prop-2-enoic acid. 2024. doi: 10.2210/pdb8piy/pdb
Buetikofer M, Orts J. NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with 2-fluoro-N-[(3-methyl-1H-pyrazol-4-yl)methyl]aniline. 2024. doi: 10.2210/pdb8qdt/pdb
Buetikofer M, Orts J. NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with 2-(methylsulfonylmethyl)-1H-benzimidazole. 2024. doi: 10.2210/pdb8qe7/pdb
Buetikofer M, Orts J. NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with 5-(1H-indol-2-l)piperazin-2-one. 2024. 19 p. doi: 10.2210/pdb8pi0/pdb
Buetikofer M, Orts J. NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with 5-(1H-indol-2-yl)pyrrolidin-2-one. 2024. doi: 10.2210/pdb8qej/pdb
Buetikofer M, Orts J. NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with7-fluoro-N,N-dimethyl-1-benzofuran-2-carboxamide. 2024. doi: 10.2210/pdb8qdn/pdb
Buetikofer M, Orts J. NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with N-[2-(5-fluoro-1H-indol-3-yl)ethyl]acetamide. 2024. doi: 10.2210/pdb8qdp/pdb
Buetikofer M, Orts J. NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with N-(3-chlorophenyl)-2-pyrrolidin-1-ylacetamide. 2024. doi: 10.2210/pdb8qei/pdb
Buetikofer M, Orts J. NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with N-(4-fluorophenyl)-2-(2-imino-1,3-thiazol-3-yl)acetamide. 2024. 19 p. doi: 10.2210/pdb8qds/pdb
Buetikofer M, Orts J. NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with N-(furan-2-ylmethyl)-1H-benzimidazol-2-amine. 2024. doi: 10.2210/pdb8qdk/pdb
Buetikofer M, Orts J. NMR2 Structure of KRAS G12V (GMPPNP bound) in complex with N-methyl-1-(1-phenylpyrazol-4-yl)methanamine. 2024. doi: 10.2210/pdb8qdw/pdb
Torres F, Stadler G, Kwiatkowski W, Orts J. A Benchmark Study of Protein-Fragment Complex Structure Calculations with NMR2. International Journal of Molecular Sciences. 2023 Sept 20;24(18):14329. doi: 10.3390/ijms241814329
Wasilewicz A, Kirchweger B, Bojkova D, Saad MJA, Langeder J, Butikofer M et al. Identification of Natural Products Inhibiting SARS-CoV-2 by Targeting Viral Proteases: A Combined in Silico and in Vitro Approach. Journal of Natural Products. 2023 Feb 24;86(2):264-275. Epub 2023 Jan 18. doi: 10.1021/acs.jnatprod.2c00843
Mohanty B, Orts J, Wang G, Nebl S, Alwan WS, Doak BC et al. Methyl probes in proteins for determining ligand binding mode in weak protein-ligand complexes. Scientific Reports. 2022 Dec;12(1):11231. doi: 10.1038/s41598-022-13561-y
1 - 20 out of 52

Advanced Isotope Labelling Methods for Integrated Structural Biology

Orts, J. (Speaker)

2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Central European Institute of Technology

Orts, J. (Speaker)

2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Central European Institute of Technology

Orts, J. (Speaker)

2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

EuChemS Division of Chemistry in Life Sciences

Orts, J. (Speaker)

2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

EUROMAR

Orts, J. (Speaker)

2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Inaugural Drug Discovery Chemistry

Orts, J. (Speaker)

2024

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Drug Discovery Chemistry

Orts, J. (Speaker)

2023 → …

Activity: Talks and presentations › Talk or oral contribution › Science to Science

New York seminar series on Biochemistry, Biophysics & Biodesign

Orts, J. (Speaker)

2023 → …

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Research Node Seminar IRB Barcelona

Orts, J. (Speaker)

2023 → …

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Natural products against SARS-CoV-2 or how to catch a butterfly?

Wasilewicz, A. (Speaker), Kirchweger, B. (Contributor), Bojkova, D. (Contributor), Abi Saad, M. J. (Contributor), Langeder, J. (Contributor), Grienke, U. (Contributor), Cinatl, J. (Contributor), Orts, J. (Contributor), Kirchmair, J. (Contributor), Rabenau, H. F. (Contributor) & Rollinger, J. M. (Contributor)

31 Aug 2022

Activity: Talks and presentations › Talk or oral contribution › Science to Science

ANZMAG Melbourne

Orts, J. (Speaker)

2022 → …

Activity: Talks and presentations › Talk or oral contribution › Science to Science

AUREM 18th NMR Users Meeting

Orts, J. (Speaker)

2022 → …

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Magnetic Moments in Central Europe

Orts, J. (Speaker)

2022 → …

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Modern Concepts in Structural Biology

Orts, J. (Speaker)

2022 → …

Activity: Talks and presentations › Talk or oral contribution › Science to Science

NMR in drug discovery

Orts, J. (Speaker)

2022 → …

Activity: Talks and presentations › Talk or oral contribution › Science to Science

RNA summer School

Orts, J. (Speaker)

2022 → …

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Workshop on Computer-Aided Drug Discovery

Orts, J. (Speaker)

2022 → …

Activity: Talks and presentations › Talk or oral contribution › Science to Science

Anti-Infectives Drug Discovery

Rollinger, J. M. (Project Lead), Dailey, L. A. (Co-Lead), Orts, J. (Co-Lead), Böttcher, T. (Co-Lead), Schmidt, M. (Co-Lead), Rademacher, C. J. H. (Co-Lead), Schützenmeister, N. (Co-Lead), Zotchev, S. (Co-Lead), Kirchmair, J. (Co-Lead) & Ortmayr, K. (Co-Lead)

1/07/25 → 30/06/29

Project: Research funding

ÖAW-Doc-Stipendium an Marie Jose Abi Saad zum Thema "Structure-based drug discovery facilitated by NMR spectroscopy: targeting the main protease of SARS-CoV-2", 24 Monate

Orts, J. (Project Lead) & Abi Saad, M. J. (Co-Lead)

1/09/23 → 31/08/25

Project: Research funding

CLAR: A calorimeter at atomic resolution

Orts, J. (Project Lead)

1/06/23 → 31/05/28

Project: Research funding

Department of Pharmaceutical Sciences

Josef-Holaubek-Platz 2 (UZA II)
1090 Wien
Room: 2F352

T: +43-1-4277-55001

julien.orts@univie.ac.at