Assoz. Prof. Dipl.-Ing. Dr. Julien Orts, M.Sc. PhD
T: +43-1-4277-55001
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Altincekic N, Jores N, Löhr F, Richter C, Ehrhardt C, Blommers MJJ et al. Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies. ACS Chemical Biology. 2024 Feb 16;19(2):563-574. Epub 2024 Jan 17. doi: 10.1021/acschembio.3c00720

Torres F, Stadler G, Kwiatkowski W, Orts J. A Benchmark Study of Protein-Fragment Complex Structure Calculations with NMR2. International Journal of Molecular Sciences. 2023 Sept 20;24(18):14329. doi: 10.3390/ijms241814329

Wasilewicz A, Kirchweger B, Bojkova D, Saad MJA, Langeder J, Butikofer M et al. Identification of Natural Products Inhibiting SARS-CoV-2 by Targeting Viral Proteases: A Combined in Silico and in Vitro Approach. Journal of Natural Products. 2023 Feb 24;86(2):264-275. Epub 2023 Jan 18. doi: 10.1021/acs.jnatprod.2c00843

Mohanty B, Orts J, Wang G, Nebl S, Alwan WS, Doak BC et al. Methyl probes in proteins for determining ligand binding mode in weak protein-ligand complexes. Scientific Reports. 2022 Dec;12(1):11231. doi: 10.1038/s41598-022-13561-y

Berg H, Martin MAW, Altincekic N, Alshamleh I, Bains JK, Blechar J et al. Comprehensive Fragment Screening of the SARS-CoV-2 Proteome Explores Novel Chemical Space for Drug Development. Angewandte Chemie International Edition. 2022 Nov 14;61(46):e202205858. doi: 10.1002/anie.202205858

Pokharna A, Torres F, Kadavath H, Orts J, Riek R. An improved, time-efficient approach to extract accurate distance restraints for NMR2structure calculation. Magnetic Resonance. 2022 Aug 1;3(2):137-144. doi: 10.5194/mr-3-137-2022

Torres F, Walser R, Kaderli J, Rossi E, Bobby R, Packer MJ et al. NMR Molecular Replacement Provides New Insights into Binding Modes to Bromodomains of BRD4 and TRIM24. Journal of Medicinal Chemistry. 2022 Apr 14;65(7):5565-5574. doi: 10.1021/acs.jmedchem.1c01703


Altincekic N, Korn SM, Qureshi NS, Dujardin M, Ninot-Pedrosa M, Abele R et al. Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications. Frontiers in Molecular Biosciences. 2021 May 10;8:653148. doi: 10.3389/fmolb.2021.653148

Strotz D, Orts J, Kadavath H, Friedmann M, Ghosh D, Olsson S et al. Protein Allostery at Atomic Resolution. Angewandte Chemie (International Edition). 2020 Dec 1;59(49):22132-22139. doi: 10.1002/anie.202008734


Torres F, Ghosh D, Strotz D, Chi CN, Davis B, Orts J. Protein-fragment complex structures derived by NMR molecular replacement. RSC Medicinal Chemistry. 2020 May;11(5):591-596. doi: 10.1039/d0md00068j

Orts J, Aulikki Wälti M, Ghosh D, Campioni S, Saupe SJ, Riek R. Rational Structure-Based Design of Fluorescent Probes for Amyloid Folds. ChemBioChem: a european journal of chemical biology. 2019 May 2;20(9):1161-1166. doi: 10.1002/cbic.201800664

Torres F, Orts J. Nuclear magnetic resonance structure-based drug design. Future Medicinal Chemistry. 2018 Oct;10(20):2373-2376. doi: 10.4155/fmc-2018-0160

Sundell GN, Arnold R, Ali M, Naksukpaiboon P, Orts J, Guntert P et al. Proteome-wide analysis of phospho-regulated PDZ domain interactions. Molecular Systems Biology. 2018 Aug;14(8):e8129. doi: 10.15252/msb.20178129

Orts J, Gossert AD. Structure determination of protein-ligand complexes by NMR in solution. Methods. 2018 Apr 1;138-139:3-25. doi: 10.1016/j.ymeth.2018.01.019


Strotz D, Orts J, Chi CN, Riek R, Vogeli B. eNORA2 Exact NOE Analysis Program: Journal of Chemical Theory and Computation. Journal of Chemical Theory and Computation. 2017 Sept;13(9):4336-4346. doi: 10.1021/acs.jctc.7b00436

Nichols PJ, Born A, Henen MA, Strotz D, Orts J, Olsson S et al. The Exact Nuclear Overhauser Enhancement: Recent Advances. Molecules. 2017 Jul 14;22(7):1176. doi: 10.3390/molecules22071176


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Drug Discovery Chemistry

Julien Orts (Speaker)

2023 → …

Activity: Talks and presentationsTalk or oral contributionScience to Science


New York seminar series on Biochemistry, Biophysics & Biodesign

Julien Orts (Speaker)

2023 → …

Activity: Talks and presentationsTalk or oral contributionScience to Science


Research Node Seminar IRB Barcelona

Julien Orts (Speaker)

2023 → …

Activity: Talks and presentationsTalk or oral contributionScience to Science


Natural products against SARS-CoV-2 or how to catch a butterfly?

Andreas Wasilewicz (Speaker), Benjamin Kirchweger (Contributor), Denisa Bojkova (Contributor), Marie Jose Abi Saad (Contributor), Julia Langeder (Contributor), Ulrike Grienke (Contributor), Jindrich Cinatl (Contributor), Julien Orts (Contributor), Johannes Kirchmair (Contributor), Holger F. Rabenau (Contributor) & Judith Maria Rollinger (Contributor)

31 Aug 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


ANZMAG Melbourne

Julien Orts (Speaker)

2022 → …

Activity: Talks and presentationsTalk or oral contributionScience to Science


AUREM 18th NMR Users Meeting

Julien Orts (Speaker)

2022 → …

Activity: Talks and presentationsTalk or oral contributionScience to Science


Magnetic Moments in Central Europe

Julien Orts (Speaker)

2022 → …

Activity: Talks and presentationsTalk or oral contributionScience to Science


Modern Concepts in Structural Biology

Julien Orts (Speaker)

2022 → …

Activity: Talks and presentationsTalk or oral contributionScience to Science


NMR in drug discovery

Julien Orts (Speaker)

2022 → …

Activity: Talks and presentationsTalk or oral contributionScience to Science


RNA summer School

Julien Orts (Speaker)

2022 → …

Activity: Talks and presentationsTalk or oral contributionScience to Science


Workshop on Computer-Aided Drug Discovery

Julien Orts (Speaker)

2022 → …

Activity: Talks and presentationsTalk or oral contributionScience to Science


Department of Pharmaceutical Sciences

Josef-Holaubek-Platz 2 (UZA II)
1090 Wien
Room: 2F352

T: +43-1-4277-55001

julien.orts@univie.ac.at