PhD students: Pharmaceutical Sciences
The PhD students are listed by division and sorted alphabetically by surname. (surname, first name)
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Division of Pharmaceutical Chemistry
PhD student Thesis (working) title Supervisor(s) Abi Saad, Marie Jose
Structure based drug discovery facilitated by NMR spectroscopy: targeting the main protease of SARS-CoV-2 Julien Orts Aichinger, Lisa Assessment of micro- and nanoplastic induced inflammatory processes by medicinal imaging Verena Pichler Alioglu, Fatih Multimodal imaging in mouse tumor models
Manfred Ogris Bayer, Sebastian Cell-type specific targeted delivery of lipid nanoparticles Christoph Rademacher Besch, Maurice Investigating allosteric modulations of the C-type lectin DC-SIGN Christoph Rademacher Cabrera Peralta, Andrea Anthar Intermolecular dynamics and allostery of human BRD4-BD1 and -BD2 Julien Orts Pharmacokinetic studies of novel modafinil analogues Thierry Langer Duman, Irem Expansion of dynamic column-based 3D cell culture methods for drug evaluation by fluorescence imaging Verena Pichler,
Manfred OgrisEder, Marlene
Immunstimulating therapeutics for evaluation on ex vivo cultured tumor tissue Manfred Ogris,
Christa SchleperErdő, Gábor Máté Application of bioinformatics in the integrative whole exome based multi-omics analysis of gastro-enteropancreatic neuroendocrine tumors for pre-diction and prognosis during diagnosis and therapy Wolfram Weckwerth,
Steffen Waldherr,
Gerhard EckerFalk, Torben Modulation of platelet biology with CLEC-2 targeted liposomes Christoph Rademacher, Fabian Pfrengle (BOKU Wien) Development of Grid-based Methods for Better Prediction of Ligand Binding in Computer-aided Molecular Design Thierry Langer,
Christian SchröderDevelopment of machine learning models for domain generalization in the chemical space Johannes Kirchmair Grabowski, Anna Identification of the cell type-specific molecular function of the NORAD-PUMILIO axis in aging Florian Kopp Grillberger, Karin A structure-based view on molecular initiating events (MIEs) related to developmental neurotoxicity (DNT) Gerhard Ecker Helmke, Palle Steen Biological and Chemical Fingerprinting for Target Prediction Gerhard Ecker Hirte, Steffen Identification and explanation of frequent-hitter behaviour of small organic molecules using Bayesian methods Johannes Kirchmair Hong, Dacheng Development of glycomimetic ligands for C-type lectin receptors Christoph Rademacher Huang, Jiahui Structure landscape analysis and functional mapping of disease-relevant mutations on SLC transporters Gerhard Ecker Jacob, Roxane Axel Development of Computational Methods for the Study and Prediction of Xenobiotic Metabolism Johannes Kirchmair, Thierry Langer Janneschütz, Jasmin Syntheses of Antiviral and Antibacterial Marine Natural Products and Analogues
Nina Schützenmeister Kandler, Julia A structure-based analysis of transporters involved in thyroid hormone homeostasis Gerhard Ecker Kogler, Lukas Production, fluorescence and radioisotope labelling of microplastics Verena Pichler Kugler, Christoph Manfred Ogris Kulterer, Elisa Sophia Manfred Ogris Lefebre, Johnathan Investigation of allosteric modulation of C-type lectins Christoph Rademacher Mazoudji, Ajouan Gerhard Ecker Millard, Marlon Design and synthesis of ligands for the muscarinic acetylcholine receptors Thierry Langer,
Verena PichlerNerín Fonz, Francho Development of a computational methodology to detect allosteric pathways in proteins and application in drug discovery Christoph Rademacher,
Zoe CourniaNguyen, Thi Thuy Anh The molecular mechanism of long non-coding RNA NORAD in cellular stress response pathways Florian Kopp Molecular Design in Ligand-based Targeted Delivery for the Development of Novel mRNA Vaccine Carriers Christoph Rademacher Toxicity Prediction of Biological Drugs Gerhard Ecker Palmacci, Vincenzo Machine learning models for the identification of compounds likely to interfere with biological assays Johannes Kirchmair Pillari, Veronica
Expanding the Chemical Space of Fluorinated Scaffolds via the Design and the Development of Novel Functionalized Nucleophilic Reagents Vittorio Pace Prosche, Aileen Characterization of the cell physiological role of the NORAD-PUMILIO axis in tissue homeostasis and regeneration during aging Florian Kopp Rahhal, Nowras Targeted delivery to Langerhans cells via Lipid Nanoparticles Christoph Rademacher Rose, Daniel Machine Learning Algorithms and Data Science Thierry Langer Schindler, Florian Metabolic characterization and natural product isolation of mutualistic plant-bacteria systems Thierry Langer,
Wolfram WeckwerthScholda, Julia The role of noncoding RNA NORAD in ER stress and the unfolded protein response Florian Kopp,
Manfred OgrisScholz, Vincent-Alexander
Metabolite Structure Prediction of Agrochemicals in Soil Johannes Kirchmair, Thierry Langer
Schwingenschlögl-Maisetschläger, Verena Establishment of a fully automated dynamic column-based three-dimensional cell culture method for radiotracer assessment Verena Pichler,
Andreas Teuschl-WollerSmajic, Aljosa Decentralized Machine Learning Approaches for Toxicity Predictions Gerhard Ecker The Macrocyclic Landscape of Solute Carrier Transporters Gerhard Ecker Spreitzer, Markus
Metabolic studies of muscarinic antagonists by LC-HRMS Thierry Langer,
Verena PichlerInvestigating the effect of bioplastic-derived micro- and nanoplastics on human health Verena Pichler Tarang, Guneet Singh Calorimeter at Atomic Resolution Julien Orts Tkaczyk, Sara
Enhancing Drug Discovery with Neural Network Potentials: Stability, Accuracy and Computational Efficiency in Free Energy Calculations
Thierry Langer, Stefan Boresch,
John Chodera (Cornell University, U.S.A.)Trenkwalder, Jessica Thierry Langer Van Hoey, Clara Development of a non-nucleoside inhibitor of enterovirus polymerases: Computer-aided design, synthesis and biological evaluation Thierry Langer Development and application of machine learning approaches integrating protein structural and ligand information for target prediction Johannes Kirchmair Weiss, Silvia Bacterial ghosts as immune-stimulating adjuvant to chemotherapy in pancreatic ductal adenocarcinoma Manfred Ogris Welsch, Matthias Johannes Kirchmair Zehetner, Theresa Thierry Langer Zhang, Huanni Computational approaches for quantifying molecular beauty in the context of drug discovery Johannes Kirchmair -
Division of Pharmaceutical Technology and Biopharmaceutics
PhD student Thesis (working) title Supervisor(s) Abdelrahman, Namarig Bolalipids as new class of penetration enhancers in dermal products Lea Ann Dailey, Victoria Klang Gausterer, Julia Clara Entwicklung und Charakterisierung von halbfesten und nanopartikulären Arzneiformen zur Anwendung in Allergologie und Otologie Franz Gabor Hämmerli, Alexander From Gene to Drug - Integrated Process Strategies for the Production of Novel Drug Delivery Systems with Drug Conjugates and Fusion Proteins Franz Gabor, Michael Wirth, Lukas Neutsch Lummerstorfer, Maria Development of nanoformulations for the delivery of prime editing ribonucleoproteins Ulrich Lächelt, Manfred Ogris Pfleger, Tanja Herbal antioxidants in dermal products: formulation, testing platforms for skin permeation and biological effects Lea Ann Dailey Phan Xuan, Thuöng Development of high entropy nanoparticles as nanozymes to improve the sensitivity of point-ofcare in vitro diagnostic tests for pre-screening of respiratory infections Lea Ann Dailey Sarne, Victoria The role of KIF5B in skeletal development and the emergence of a skeletal dysplasia Winfried Neuhaus Schwarzinger, Jacqueline Inhalation of natural products against lung infection - Biopharmaceutical profiling of selected natural product sample sets and determination of the inhalation formulation approach Lea Ann Dailey Shahir, Mehri Glycomimetic-based targeted delivery of antigens to Langerhans cells for immune activation and the indication of tolerance Christoph Rademacher Steiner, Katja Phospholipid-based emulsifiers for sunscreen development: impact of UVA and effect on skin properties in vitro, ex vivo and in vivo Lea Ann Dailey, Victoria Klang Wimmer, Lukas Enhancing micro- and nanoplastics research: Using pharmaceutical methodologies to develop reference micro- and nanoplastics for studying the impacts of plastics on human health Lea Ann Dailey Xue, Zian Development of CRISPR/Cas9-sgRNA Ribo-nucleoprotein (RNP) Delivery Systems by Modifying Artificial Peptide Carriers and Nucleic Acid Component Ulrich Lächelt,
Lea Ann Dailey -
Division of Pharmacology and Toxicology
PhD student Thesis (working) title Supervisor(s) Balasubramanian, Hari Baskar Identification of the metabolites associated with a dietary intervention that protect against hypertension-induced cerebrovascular injury Marietta Zille Baltov, Bozhidar Borislavov 2D and 3D cultures of stem cell derived cardiac cells on patterned cell culture surfaces for cardiotox studies Steffen Hering Friesacher, Theres Eva Novel approaches to investigate the regulation of G-protein coupled inward rectifier K+ channels by Gβγ Anna Weinzinger Grundtner, Sabrina Chronic pain a disease, which is not well understood on the molecular level Manuela Schmidt, Christian Studenik Kampleitner, Carina Identifying the molecular and cellular pathways associated with bone fracture healing with and without biomaterials in healthy and osteoporotic bone Oskar Hoffmann, Klaus Wirth Netzer, Michael Electrophysiological characterization and proof of principle cardiotoxicity screenings of cardioids Steffen Hering Pasokh, Amir Targeting the gut-brain axis in hypertension-induced brain injury Marietta Zille -
Division of Pharmacognosy
PhD student Thesis (working) title Supervisor(s) Adelsberger, Sigrid Inhalation of natural products against lung infections – extraction, isolation and analysis of selected natural product sample sets and analytical evaluation of inhalable formulations Ulrike Grienke Brenner, Martin Causal role of altered cellular energy metabolism for immunomodulation by selected natural products Elke Heiß, Wolfram Weckwerth Coffey, Christine Identifying Nature’s c(h)AMPions: Func-tional and mechanistic characterization of natural product derivatives as PDE4 inhibi-tors. Verena Dirsch Eichenauer, Elisabeth Traditional herbal medicines for wound healing: phytochemical profiling and activity screening Sabine Glasl-Tazreiter, Elke Heiß Haiss, Patricia Examination of the preventive/therapeutic potential of natural products in atherosclerotic and proliferative vascular wall changes using cell-based models Verena Dirsch Malfent, Fabian Discovery of novel natural products from bacteria isolated from environmental sources with conventional and genome mining approaches Sergey Zotchev Redl, Martina Identifying and dissecting health promoting natural products for healthy ageing in Caenorhabditis elegans Judith Rollinger Schwarz, Patrik Discovery and biological evaluation of novel natural ligands for the nuclear receptor RORγ Verena Dirsch, Elke Heiß Sosa Cabrera, Shara Natalia AMP(K)lifying Nrf2 - Digging into the fine‐tuned control of Nrf2‐mediated cellular responses by AMPK Elke Heiß Vignolle, Anna (née Stich) Exploration of the secondary metabolite biosynthesis potential of the bacteria isolated from the rhizosphere of the medicinal plant Leontopodium nivale Sergey Zotchev Theiler, Barbara Medicinal Plants against Diabetes Mellitus Search for New Antidiabetic Agents from Traditional Medicines Sabine Glasl-Tazreiter