PhD students: Pharmaceutical Sciences
The PhD students are listed by division and sorted alphabetically by surname. (surname, first name)
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Division of Pharmaceutical Chemistry
PhD student Thesis (working) title Supervisor(s) Abi Saad, Marie Jose
Structure based drug discovery facilitated by NMR spectroscopy: targeting the main protease of SARS-CoV-2 Julien Orts Aichinger, Lisa Assessment of micro- and nanoplastic induced inflammatory processes by medicinal imaging Verena Pichler Alioglu, Fatih Multimodal imaging in mouse tumor models
Manfred Ogris Bayer, Sebastian Cell-type specific targeted delivery of lipid nanoparticles Christoph Rademacher Cabrera Peralta, Andrea Anthar Intermolecular dynamics and allostery of human BRD4-BD1 and -BD2 Julien Orts Pharmacokinetic studies of novel modafinil analogues Thierry Langer Dragačević, Vladimir
Synthesis, structural and functional characterisation of novel atypical dopamine reuptake inhibitors with two chiral centres" Thierry Langer Duman, Irem Expansion of dynamic column-based 3D cell culture methods for drug evaluation by fluorescence imaging Verena Pichler, Manfred Ogris Eder, Marlene
Manfred Ogris Erdő, Gábor Máté Application of integrative bioinformatics in the analysis of whole exome based multiomics and imaging for prediction and prognosis in the diagnosis and therapeutic treatment of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) Wolfram Weckwerth, Steffen Waldherr, Gerhard Ecker Falk, Torben Christoph Rademacher Development of Grid-based Methods for Better Prediction of Ligand Binding in Computer-aided Molecular Design Thierry Langer Development of machine learning models for domain generalization in the chemical space Johannes Kirchmair Garon, Arthur Philippe Towards Next Generation Pharmacophore Models Thierry Langer Grabowski, Anna Identification of the cell type-specific molecular function of the NORAD-PUMILIO axis in aging Florian Kopp The Macrocyclic Landscape of Solute Carrier Transporters Gerhard Ecker Grillberger, Karin A structure-based view on molecular initiating events (MIEs) related to developmental neurotoxicity (DNT) Gerhard Ecker Helmke, Palle Steen Biological and Chemical Fingerprinting for Target Prediction Gerhard Ecker Hirte, Steffen Identification and explanation of frequent-hitter behaviour of small organic molecules using Bayesian methods Johannes Kirchmair Hong, Dacheng Development of glycomimetic ligands for C-type lectin receptors Christoph Rademacher Huang, Jiahui Structure landscape analysis and functional mapping of disease-relevant mutations on SLC transporters Gerhard Ecker Jacob, Roxane Axel Deep Learning Methods for the Prediction of the Metabolic Fate of Small Organic Molecules Johannes Kirchmair Syntheses of Antiviral and Antibacterial Marine Natural Products and Analogues
Nina Schützenmeister Kandler, Julia A structure-based view on transporters involved in thyroid hormone homeostasis Gerhard Ecker Kogler, Lukas Developing new strategies for the production and labelling of micro- and nano-plastic Verena Pichler Kulterer, Elisa Sophia Manfred Ogris Lefebre, Johnathan Investigation of allosteric modulation of C-type lectins Christoph Rademacher Schwingenschlögl-Maisetschläger, Verena Establishment of a fully automated dynamic column-based three-dimensional cell culture method for radiotracer assessment Verena Pichler Computational approaches for the rational design of Inflammasome inhibitors Thierry Langer, Ugo Perricone Millard, Marlon Design and synthesis of ligands for the muscarinic acetylcholine receptors Thierry Langer, Verena Pichler Müller, Carina Proteomic characterization of the dopamine transporter by mass spectrometry and the impact on the dopaminergic system by cognitive enhancers Thierry Langer, Ernst Urban Nerín Fonz, Francho Development of a computational methodology to detect allosteric pathways in proteins and application in drug discovery Christoph Rademacher, Zoe Cournia Nguyen, Thi Thuy Anh The molecular mechanism of long non-coding RNA NORAD in cellular stress response pathways Florian Kopp Molecular Design in Ligand-based Targeted Delivery for the Development of Novel mRNA Vaccine Carriers Christoph Rademacher Toxicity Prediction of Biological Drugs Gerhard Ecker Palmacci, Vincenzo Machine learning models for the identification of compounds likely to interfere with biological assays Johannes Kirchmair Permann, Christian
Molecular Informatics of Next Generation Macrocycles" Thierry Langer Pillari, Veronica
Expanding the Chemical Space of Fluorinated Scaffolds via the Design and the Development of Novel Functionalized Nucleophilic Reagents Vittorio Pace Prosche, Aileen Characterization of the cell physiological role of the NORAD-PUMILIO axis in tissue homeostasis and regeneration during aging Florian Kopp Rahhal, Nowras Targeted delivery to Langerhans cells via Lipid Nanoparticles Christoph Rademacher Rose, Daniel Machine Learning Algorithms and Data Science Thierry Langer Schindler, Florian Metabolic characterization and natural product isolation of mutualistic plant-bacteria systems Thierry Langer, Wolfram Weckwerth Scholda, Julia The role of noncoding RNA NORAD in ER stress and the unfolded protein response Florian Kopp, Manfred Ogris Scholz, Vincent-Alexander
Johannes Kirchmair Simic, Stefan Pharmacokinetic profiling of novel anti-Alzheimer’s agents Thierry Langer Smajic, Aljosa Decentralized Machine Learning Approaches for Toxicity Predictions Gerhard Ecker Spreitzer, Markus
Metabolic studies of muscarinic antagonists by LC-HRMS Thierry Langer Investigating the effect of bioplastic-derived micro- and nanoplastics on human health Verena Pichler Tkaczyk, Sara
Thierry Langer Van Hoey, Clara Development of a non-nucleoside inhibitor of enterovirus polymerases: Computer-aided design, synthesis and biological evaluation Thierry Langer Development and application of machine learning approaches integrating protein structural and ligand information for target prediction Johannes Kirchmair Watzinger, Simon Verena Pichler Weiss, Silvia Bacterial ghosts as immune-stimulating adjuvant to chemotherapy in pancreatic ductal adenocarcinoma Manfred Ogris Zhang, Huanni Development of computational approaches for quantifying molecular beauty in the context of drug discovery Johannes Kirchmair -
Division of Pharmaceutical Technology and Biopharmaceutics
PhD student Thesis (working) title Supervisor(s) Abdelrahman Abdelltif Abdelrahman, Namarig Bolalipids as new class of penetration enhancers in dermal products Lea Ann Dailey, Victoria Klang Gausterer, Julia Clara Entwicklung und Charakterisierung von halbfesten und nanopartikulären Arzneiformen zur Anwendung in Allergologie und Otologie Franz Gabor Hämmerli, Alexander From Gene to Drug - Integrated Process Strategies for the Production of Novel Drug Delivery Systems with Drug Conjugates and Fusion Proteins Franz Gabor, Michael Wirth, Lukas Neutsch Li, Feng Study on different biocompatible pulmonary drug delivery systems for the enhanced treatment of respiratory tuberculosis infections Lea Ann Dailey Lummerstorfer, Maria Development of nanoformulations for therapeutic biomolecules and genome-editing components Ulrich Lächelt Pfleger, Tanja Panax ginseng extract as herbal antioxidant in dermal preparations: technological aspects and in vitro effects on human dermal primary cell Lea Ann Dailey Phan Xuan, Thuöng Development of high entropy nanoparticles as nanozymes to improve the sensitivity of point-ofcare in vitro diagnostic tests for pre-screening of respiratory infections Lea Ann Dailey Sarne, Victoria The role of KIF5B in skeletal development and the emergence of a skeletal dysplasia Winfried Neuhaus Schwarzinger, Jacqueline Inhalation of natural products against lung infection - Biopharmaceutical profiling of selected natural product sample sets and determination of the inhalation formulation approach Lea Ann Dailey Shahir, Mehri Glycomimetic-based targeted delivery of antigens to Langerhans cells for immune activation and the indication of tolerance Christoph Rademacher Steiner, Katja Phospholipid-based emulsifiers for sunscreen development: impact of UVA and effect on skin properties in vitro, ex vivo and in vivo Lea Ann Dailey, Victoria Klang Wimmer, Lukas Enhancing micro- and nanoplastics research: Using pharmaceutical methodologies to develop reference micro- and nanoplastics for studying the impacts of plastics on human health Lea Ann Dailey Xue, Zian Development of a Cas9-sgRNA Ribonucleoprotein (RNP) Delivery System for Targeting KRAS-G12D in Colorectal Cancer Ulrich Lächelt -
Division of Pharmacology and Toxicology
PhD student Thesis (working) title Supervisor(s) Abdelaziz, Ramadan Faried Abbas Lysosomal proteases impact on cancer and infectious diseases Christian Studenik, Tamer Salem Baltov, Bozhidar Borislavov 2D and 3D cultures of stem cell derived cardiac cells on patterned cell culture surfaces for cardiotox studies Steffen Hering Friesacher, Theres Eva Novel approaches to investigate the regulation of G-protein coupled inward rectifier K+ channels by Gβγ Anna Weinzinger Garifulina, Aleksandra Modulation of Ligand-Gated Ion Channels by Peptides and Low-Molecular-Weight Compounds Steffen Hering Grundtner, Sabrina Chronic pain a disease, which is not well understood on the molecular level Manuela Schmidt, Christian Studenik Huber, Anna Magdalena Generation of functionally active neurons from fibroblasts derived from Rett syndrome patients via a non-integrating reprogramming strategy for in vitro protein replacement therapy Franco Laccone, Christian Studenik Kampleitner, Carina Identifying the molecular and cellular pathways associated with bone fracture healing with and without biomaterials in healthy and osteoporotic bone Oskar Hoffmann, Klaus Wirth Netzer, Michael Electrophysiological characterization and proof of principle cardiotoxicity screenings of cardioids Steffen Hering Pasokh, Amir Targeting the gut-brain axis in hypertension-induced brain injury Marietta Zille -
Division of Pharmacognosy
PhD student Thesis (working) title Supervisor(s) Adelsberger, Sigrid Inhalation of natural products against lung infections – extraction, isolation and analysis of selected natural product sample sets and analytical evaluation of inhalable formulations Ulrike Grienke Bahiraii, Sheyda Metabolic immunomodulation by natural products with focus on macrophage polarization Elke Heiß Brenner, Martin Causal role of altered cellular energy metabolism for immunomodulation by selected natural products Elke Heiß, Wolfram Weckwerth Coffey, Christine Identifying Nature’s c(h)AMPions: Func-tional and mechanistic characterization of natural product derivatives as PDE4 inhibi-tors. Verena Dirsch Eichenauer, Elisabeth Traditional herbal medicines for wound healing: phytochemical profiling and activity screening Sabine Glasl-Tazreiter, Elke Heiß Haiss, Patricia Examination of the preventive/therapeutic potential of natural products in atherosclerotic and proliferative vascular wall changes using cell-based models Verena Dirsch Malfent, Fabian Discovery of novel natural products from bacteria isolated from environmental sources with conventional and genome mining approaches Sergey Zotchev Redl, Martina Identifying and dissecting health promoting natural products for healthy ageing in Caenorhabditis elegans Judith Rollinger Schwarz, Patrik Discovery and biological evaluation of novel natural ligands for the nuclear receptor RORγ Verena Dirsch, Elke Heiß Sosa Cabrera, Shara Natalia AMP(K)lifying Nrf2 - Digging into the fine‐tuned control of Nrf2‐mediated cellular responses by AMPK Elke Heiß Vignolle, Anna (née Stich) Exploration of the secondary metabolite biosynthesis potential of the bacteria isolated from the rhizosphere of the medicinal plant Leontopodium nivale Sergey Zotchev Theiler, Barbara Medicinal Plants against Diabetes Mellitus Search for New Antidiabetic Agents from Traditional Medicines Sabine Glasl-Tazreiter Wasilewicz, Andreas Natural products against acute respiratory infections Judith Rollinger, Johannes Kirchmair