PhD students: Pharmaceutical Sciences
The PhD students are listed by division and sorted alphabetically by surname. (surname, first name)
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Division of Pharmaceutical Chemistry
PhD student Thesis (working) title Supervisor(s) Abu Shehab, Uday Towards tailored domain adaptation in drug discovery applications Johannes Kirchmair Aichinger, Lisa Assessment of micro- and nanoplastic induced inflammatory processes by medicinal imaging Verena Pichler, Cecile Philippe Alioglu, Fatih Multimodal imaging in mouse tumor models
Manfred Ogris Bayer, Sebastian Cell-type specific targeted delivery of lipid nanoparticles Christoph Rademacher Becker, Micha Rolf Stefan Anti-infectives from antagonistic interactions of Pseudomonas and Candida Thomas Böttcher Besch, Maurice Investigating allosteric modulations of the C-type lectin DC-SIGN Christoph Rademacher Cabrera Peralta, Andrea Anthar Intermolecular dynamics and allostery of human BRD4-BD1 and -BD2 Julien Orts Cerimagic, Tarik Data Imputation Approaches for Missing Bioactivity Values of Compounds Across a Heterologous Target Space Gerhard F. Ecker Ceylan, Irem Non-carbohydrate-based glycomimetic-based inhibition of P. aeruginosa biofilm formation Christoph Rademacher Duman, Irem Expansion of dynamic column-based 3D cell culture methods for drug evaluation by fluorescence imaging Verena Pichler,
Manfred OgrisEder, Marlene
Immunstimulating therapeutics for evaluation on ex vivo cultured tumor tissue Manfred Ogris,
Christa SchleperErdő, Gábor Máté Application of bioinformatics in the integrative whole exome based multi-omics analysis of gastro-enteropancreatic neuroendocrine tumors for pre-diction and prognosis during diagnosis and therapy Wolfram Weckwerth,
Steffen Waldherr,
Gerhard EckerFalk, Torben Modulation of platelet biology with CLEC-2 targeted liposomes Christoph Rademacher, Fabian Pfrengle (BOKU Wien) Development of Grid-based Methods for Better Prediction of Ligand Binding in Computer-aided Molecular Design Thierry Langer,
Christian SchröderFoil, Daniel Harrison Expanding the in silico toolbox for pesticide genotoxicity in regulatory toxicology Johannes Kirchmair, Thierry Langer Development of machine learning models for domain generalization in the chemical space Johannes Kirchmair Gashi, Laureta Targeting GABAA-receptors and the GABAergic system in the central nucleus of the amygdala in Alcohol Use Disorder Sophia Khom-Steinkellner,
Marietta ZilleGrabowski, Anna Identification of the cell type-specific molecular function of the NORAD-PUMILIO axis in aging Florian Kopp Grillberger, Karin A structure-based view on molecular initiating events (MIEs) related to developmental neurotoxicity (DNT) Gerhard Ecker Hehenberger, Stefanie Drug therapy- and patient safety in ileostomy patients: clinical- pharmaceutical measures Irene Lagoja Helmke, Palle Steen Biological and Chemical Fingerprinting for Target Prediction Gerhard Ecker Hirsch, Stefanie Total synthesis of antimicrobial natural products and analogues Nina Schützenmeister Hirte, Steffen Identification and explanation of frequent-hitter behaviour of small organic molecules using Bayesian methods Johannes Kirchmair Hong, Dacheng Development of glycomimetic ligands for C-type lectin receptors Christoph Rademacher Jacob, Roxane Axel Development of Computational Methods for the Study and Prediction of Xenobiotic Metabolism Johannes Kirchmair, Thierry Langer Janneschütz, Jasmin Syntheses of Antiviral and Antibacterial Marine Natural Products and Analogues
Nina Schützenmeister Kandler, Julia A structure-based analysis of transporters involved in thyroid hormone homeostasis Gerhard Ecker Khalid, Khurram Sophia Khom-Steinkellner Kogler, Lukas Production, fluorescence and radioisotope labelling of microplastics Verena Pichler Kugler, Christoph Development of peptide targeted drug carrier for multimodal imaging Manfred Ogris Kulterer, Elisa Sophia Molecularly controlled mRNA vectors as breast cancer therapeutics Manfred Ogris Lefebre, Johnathan Investigation of allosteric modulation of C-type lectins Christoph Rademacher Markhof, Alina Christoph Rademacher Mazoudji, Ajouan InSilify DrugTox - A broad computational retrospective analysis of pharmaceutical scientific advice and authorization data to evaluate the predictivity and usability of toxicological in silico models in drug development Gerhard Ecker Nerín Fonz, Francho Development of a computational methodology to detect allosteric pathways in proteins and application in drug discovery Christoph Rademacher,
Zoe CourniaNoordmann, Neele Noncoding RNA in stress-related metabolic disease: physiological role and therapeutic application Florian Kopp Oikonomou, Athanasios Computer-guided identification and optimization of small molecules targeting Pseudomonas and Candida Johannes Kirchmair Omahen, Blaž New antifungal strategy against invasive Candida infections Julien Orts Parianou, Anna Sofia Christoph Rademacher Rose, Daniel Development of Machine Learning-based Methods for Virtual Screening with 3D Pharmacophore Models Thierry Langer, Johannes Kirchmair Schindler, Florian Metabolic characterization and natural product isolation of mutualistic plant-bacteria systems Thierry Langer,
Wolfram WeckwerthScholz, Vincent-Alexander
Metabolite Structure Prediction of Agrochemicals in Soil Johannes Kirchmair, Thierry Langer
Schwab, Max Albert Studying and Overcoming the H2O2-Induced Resistance towards Epidermal Growth Factor Receptor (EGFR) Inhibitors in Advanced Non-Small Cell Lung Cancer (NSCLC) David Konrad Schwingenschlögl-Maisetschläger, Verena Establishment of a fully automated dynamic column-based three-dimensional cell culture method for radiotracer assessment Verena Pichler,
Andreas Teuschl-WollerSehic, Nejra The Macrocyclic Landscape of Solute Carrier Transporters Gerhard Ecker Simic, Stefan Pharmacokinetic profiling of novel anti-Alzheimer’s agents Thierry Langer Skowrońska, Izabela Ecologically Benign Total Synthesis of Naturally Occurring C-Glycosidic Compounds and Analogues Nina Schützenmeister Metabolic studies of muscarinic antagonists by LC-HRMS Thierry Langer,
Verena Pichler, Judith WackerligInvestigating the effect of bioplastic-derived micro- and nanoplastics on human health Verena Pichler Tarang, Guneet Singh Calorimeter at Atomic Resolution Julien Orts Tkaczyk, Sara
Enhancing Drug Discovery with Neural Network Potentials: Stability, Accuracy and Computational Efficiency in Free Energy Calculations
Thierry Langer,
Stefan Boresch,
John Chodera (Cornell University, U.S.A.)Trenkwalder, Jessica Computational Target Prediction in Synucleinopathies Thierry Langer Development and application of machine learning approaches integrating protein structural and ligand information for target prediction Johannes Kirchmair Welsch, Matthias Representational alignment in cheminformatics Johannes Kirchmair, Thierry Langer Wiese, Christopher Albert Thierry Langer Zhang, Huanni Computational approaches for quantifying molecular beauty in the context of drug discovery Johannes Kirchmair, Thierry Langer Zusag, Markus Clinical relevance and cost-effectiveness of pharmacogenomic testing in outpatient pharmacotherapy Florian Kopp -
Division of Pharmaceutical Technology and Biopharmaceutics
PhD student Thesis (working) title Supervisor(s) Abdelrahman, Namarig Bolalipids as new class of penetration enhancers in dermal products Lea Ann Dailey
Victoria KlangLummerstorfer, Maria Development of nanoformulations for the delivery of prime editing ribonucleoproteins Ulrich Lächelt
Manfred OgrisNguyen Hoang, My Vanessa The impact of micro- and nanoplastics on lung model systems Lea Ann Dailey Pfleger, Tanja Herbal antioxidants in dermal products: formulation, testing platforms for skin permeation and biological effects Lea Ann Dailey
Victoria KlangSarne, Victoria The role of KIF5B in skeletal development and the emergence of a skeletal dysplasia Winfried Neuhaus Schmolz, Jakob Josef Exploring polymer-based hybrid delivery strategies for transdermal hormone replacement therapy to improve clinical practice Victoria Klang Schwarzinger, Jacqueline Inhalation of natural products against lung infection - Biopharmaceutical profiling of selected natural product sample sets and determination of the inhalation formulation approach Lea Ann Dailey Wurster, Leonie Performance-enhancing formulations for antifungal and antibacterial therapies Lea Ann Dailey Xue, Zian Development of CRISPR/Cas9-sgRNA Ribo-nucleoprotein (RNP) Delivery Systems by Modifying Artificial Peptide Carriers and Nucleic Acid Component Ulrich Lächelt,
Lea Ann Dailey -
Division of Pharmacology and Toxicology
PhD student Thesis (working) title Supervisor(s) Balasubramanian, Hari Baskar Identification of the metabolites associated with a dietary intervention that protect against hypertension-induced cerebrovascular injury Marietta Zille Eder, Sebastian Johannes Improving Accuracy and Reproducibility in de novo (Meta-)Proteomics Through AI and Database-Independent FDR Estimation Manuela Schmidt Kampleitner, Carina Identifying the molecular and cellular pathways associated with bone fracture healing with and without biomaterials in healthy and osteoporotic bone Oskar Hoffmann, Klaus Wirth Karic, Medina Investigating Lysosomal Proteases in the Invasion and Metastasis of Pituitary Adenocarcinoma Mohammed Aufy Netzer, Michael Electrophysiological characterization and proof of principle cardiotoxicity screenings of cardioids Steffen Hering Nguyen, Van Phuong Potassium Kv10.1 Channel-Lipid Dysregulation in Diseases Anna Weinzinger Pasokh, Amir Targeting the gut-brain axis in hypertension-induced brain injury Marietta Zille Steshin, Ilia Developments of pharmacotherapies for GIRK linked diseases Anna Weinzinger Thivaios, Christos Athanasios Proteome-level identification of mechanism of action (MoA) of natural compounds Manuela Schmidt -
Division of Pharmacognosy
PhD student Thesis (working) title Supervisor(s) Bertaina, Lorenza Targeting RORγ(t) with natural and semisynthetic ligands Verena Dirsch Brenner, Martin The role of metabolic shifts for natural product-induced immunomodulation - Focus on Mass Spectrometry Elke Heiß, Wolfram Weckwerth Coffey, Christine Identifying Nature’s c(h)AMPions: Functional and mechanistic characterization of natural product derivatives as PDE4 inhibitors. Verena Dirsch, Alexander Perhal Gafriller, Johannes Mycochemical and phytopathological investigations in the search for biopesticides against Ramularia mali Judith Rollinger
Thomas BöttcherHaiss, Patricia Examination of the preventive/therapeutic potential of natural products in atherosclerotic and proliferative vascular wall changes using cell-based models Verena Dirsch Loukatou, Spyridoula Artificial intelligence for the targeted identification and isolation of anti-infective natural products Judith Rollinger Osswald, Xenia Targeting siderophore re-uptake as a strategy to fight infections caused by P. aeruginosa Sergey B. Zotchev Redl, Martina Identifying and dissecting health promoting natural products for healthy ageing in Caenorhabditis elegans Judith Rollinger Reyes Lopez, Celeste Investigating and engineering the biosynthesis of glycopeptide antibiotics from the newly discovered type VI family Sergey B. Zotchev Riffelsberger, Katharina Discovery and Characterisation of Natural Products as Ligands for Nuclear Receptors using Experimental and In Silico Approaches Verena Dirsch, Johannes Kirchmair Schranzer, Nicole Mining of Streptomyces bacteria for bioactive secondary metabolites Sergey B. Zotchev Schuler, Eva Dissecting Metabolic Regulatory Mechanisms in Cancer Recurrence: Non-targeted metabolomics of quiescent cancer cells after genetic perturbation of metabolic regulators Karin Ortmayr Sosa Cabrera, Shara Natalia AMP(K)lifying Nrf2 - Digging into the fine‐tuned control of Nrf2‐mediated cellular responses by AMPK Elke Heiß Stenzl, Marlis Alrike Combined phenotypic and metabolome profiling for accelerated
compound characterizationKarin Ortmayr Theiler, Barbara Medicinal Plants against Diabetes Mellitus Search for New Antidiabetic Agents from Traditional Medicines Sabine Glasl-Tazreiter Waltenberger, Eva Discovery of natural products targeting metabolic processes Judith M. Rollinger