PhD students: Pharmaceutical Sciences
The PhD students are listed by division and sorted alphabetically by surname. (surname, first name)
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Division of Pharmaceutical Chemistry
PhD student Thesis (working) title Supervisor(s) Abu Shehab, Uday Target prediction and virtual screening methods in the natural products space Johannes Kirchmair Aichinger, Lisa Assessment of micro- and nanoplastic induced inflammatory processes by medicinal imaging Verena Pichler, Cecile Philippe Alioglu, Fatih Multimodal imaging in mouse tumor models
Manfred Ogris Bayer, Sebastian Cell-type specific targeted delivery of lipid nanoparticles Christoph Rademacher Besch, Maurice Investigating allosteric modulations of the C-type lectin DC-SIGN Christoph Rademacher Bocanegra Gomez, Laura Manfred Ogris Cabrera Peralta, Andrea Anthar Intermolecular dynamics and allostery of human BRD4-BD1 and -BD2 Julien Orts Cerimagic, Tarik Data Imputation Approaches for Missing Bioactivity Values of Compounds Across a Heterologous Target Space Gerhard F. Ecker Duman, Irem Expansion of dynamic column-based 3D cell culture methods for drug evaluation by fluorescence imaging Verena Pichler,
Manfred OgrisEder, Marlene
Immunstimulating therapeutics for evaluation on ex vivo cultured tumor tissue Manfred Ogris,
Christa SchleperErdő, Gábor Máté Application of bioinformatics in the integrative whole exome based multi-omics analysis of gastro-enteropancreatic neuroendocrine tumors for pre-diction and prognosis during diagnosis and therapy Wolfram Weckwerth,
Steffen Waldherr,
Gerhard EckerFalk, Torben Modulation of platelet biology with CLEC-2 targeted liposomes Christoph Rademacher, Fabian Pfrengle (BOKU Wien) Development of Grid-based Methods for Better Prediction of Ligand Binding in Computer-aided Molecular Design Thierry Langer,
Christian SchröderFoil, Daniel Harrison Expanding the in silico toolbox for pesticide genotoxicity in regulatory toxicology Johannes Kirchmair, Thierry Langer Development of machine learning models for domain generalization in the chemical space Johannes Kirchmair Gashi, Laureta Sophia Khom-Steinkellner Grabowski, Anna Identification of the cell type-specific molecular function of the NORAD-PUMILIO axis in aging Florian Kopp Grillberger, Karin A structure-based view on molecular initiating events (MIEs) related to developmental neurotoxicity (DNT) Gerhard Ecker Hehenberger, Stefanie Drug therapy- and patient safety in ileostomy patients: clinical- pharmaceutical measures Irene Lagoja Helmke, Palle Steen Biological and Chemical Fingerprinting for Target Prediction Gerhard Ecker Hirte, Steffen Identification and explanation of frequent-hitter behaviour of small organic molecules using Bayesian methods Johannes Kirchmair Hong, Dacheng Development of glycomimetic ligands for C-type lectin receptors Christoph Rademacher Jacob, Roxane Axel Development of Computational Methods for the Study and Prediction of Xenobiotic Metabolism Johannes Kirchmair, Thierry Langer Janneschütz, Jasmin Syntheses of Antiviral and Antibacterial Marine Natural Products and Analogues
Nina Schützenmeister Kandler, Julia A structure-based analysis of transporters involved in thyroid hormone homeostasis Gerhard Ecker Kogler, Lukas Production, fluorescence and radioisotope labelling of microplastics Verena Pichler Kugler, Christoph Development of peptide targeted drug carrier for multimodal imaging Manfred Ogris Kulterer, Elisa Sophia Molecularly controlled mRNA vectors as breast cancer therapeutics Manfred Ogris Lefebre, Johnathan Investigation of allosteric modulation of C-type lectins Christoph Rademacher Markhof, Alina Christoph Rademacher Mazoudji, Ajouan InSilify DrugTox - A broad computational retrospective analysis of pharmaceutical scientific advice and authorization data to evaluate the predictivity and usability of toxicological in silico models in drug development Gerhard Ecker Nerín Fonz, Francho Development of a computational methodology to detect allosteric pathways in proteins and application in drug discovery Christoph Rademacher,
Zoe CourniaNguyen, Thi Thuy Anh The molecular mechanism of long non-coding RNA NORAD in cellular stress response pathways Florian Kopp Molecular Design in Ligand-based Targeted Delivery for the Development of Novel mRNA Vaccine Carriers Christoph Rademacher Oikonomou, Athanasios Johannes Kirchmair Toxicity Prediction of Biological Drugs Gerhard Ecker Palmacci, Vincenzo Machine learning models for the identification of compounds likely to interfere with biological assays Johannes Kirchmair Parianou, Anna Sofia Christoph Rademacher Rahhal, Nowras Targeted delivery to Langerhans cells via Lipid Nanoparticles Christoph Rademacher Rose, Daniel Development of Machine Learning-based Methods for Virtual Screening with 3D Pharmacophore Models Thierry Langer, Johannes Kirchmair Schindler, Florian Metabolic characterization and natural product isolation of mutualistic plant-bacteria systems Thierry Langer,
Wolfram WeckwerthScholz, Vincent-Alexander
Metabolite Structure Prediction of Agrochemicals in Soil Johannes Kirchmair, Thierry Langer
Schwingenschlögl-Maisetschläger, Verena Establishment of a fully automated dynamic column-based three-dimensional cell culture method for radiotracer assessment Verena Pichler,
Andreas Teuschl-WollerSehic, Nejra The Macrocyclic Landscape of Solute Carrier Transporters Gerhard Ecker Simic, Stefan Pharmacokinetic profiling of novel anti-Alzheimer’s agents Thierry Langer Skowrońska, Izabela Ecologically Benign Total Synthesis of Naturally Occurring C-Glycosidic Compounds and Analogues Nina Schützenmeister Metabolic studies of muscarinic antagonists by LC-HRMS Thierry Langer,
Verena Pichler, Judith WackerligInvestigating the effect of bioplastic-derived micro- and nanoplastics on human health Verena Pichler Tarang, Guneet Singh Calorimeter at Atomic Resolution Julien Orts Tkaczyk, Sara
Enhancing Drug Discovery with Neural Network Potentials: Stability, Accuracy and Computational Efficiency in Free Energy Calculations
Thierry Langer, Stefan Boresch,
John Chodera (Cornell University, U.S.A.)Trenkwalder, Jessica Computational Target Prediction in Synucleinopathies Thierry Langer Van Hoey, Clara Development of a non-nucleoside inhibitor of enterovirus polymerases: Computer-aided design, synthesis and biological evaluation Thierry Langer Development and application of machine learning approaches integrating protein structural and ligand information for target prediction Johannes Kirchmair Welsch, Matthias Representational alignment in cheminformatics Johannes Kirchmair, Thierry Langer Zhang, Huanni Computational approaches for quantifying molecular beauty in the context of drug discovery Johannes Kirchmair, Thierry Langer Zusag, Markus Florian Kopp -
Division of Pharmaceutical Technology and Biopharmaceutics
PhD student Thesis (working) title Supervisor(s) Abdelrahman, Namarig Bolalipids as new class of penetration enhancers in dermal products Lea Ann Dailey
Victoria KlangHämmerli, Alexander From Gene to Drug - Integrated Process Strategies for the Production of Novel Drug Delivery Systems with Drug Conjugates and Fusion Proteins Franz Gabor
Michael Wirth
Lukas NeutschLummerstorfer, Maria Development of nanoformulations for the delivery of prime editing ribonucleoproteins Ulrich Lächelt
Manfred OgrisNguyen Hoang, My Vanessa The impact of micro- and nanoplastics on lung model systems Lea Ann Dailey Pfleger, Tanja Herbal antioxidants in dermal products: formulation, testing platforms for skin permeation and biological effects Lea Ann Dailey
Victoria KlangSarne, Victoria The role of KIF5B in skeletal development and the emergence of a skeletal dysplasia Winfried Neuhaus Schmolz, Jakob Josef Exploring polymer-based hybrid delivery strategies for transdermal hormone replacement therapy to improve clinical practice Victoria Klang Schwarzinger, Jacqueline Inhalation of natural products against lung infection - Biopharmaceutical profiling of selected natural product sample sets and determination of the inhalation formulation approach Lea Ann Dailey Shahir, Mehri Glycomimetic-based targeted delivery of antigens to Langerhans cells for immune activation and the indication of tolerance Christoph Rademacher Wimmer, Lukas Enhancing micro- and nanoplastics research: Using pharmaceutical methodologies to develop reference micro- and nanoplastics for studying the impacts of plastics on human health Lea Ann Dailey Wurster, Leonie Lea Ann Dailey Xue, Zian Development of CRISPR/Cas9-sgRNA Ribo-nucleoprotein (RNP) Delivery Systems by Modifying Artificial Peptide Carriers and Nucleic Acid Component Ulrich Lächelt,
Lea Ann Dailey -
Division of Pharmacology and Toxicology
PhD student Thesis (working) title Supervisor(s) Balasubramanian, Hari Baskar Identification of the metabolites associated with a dietary intervention that protect against hypertension-induced cerebrovascular injury Marietta Zille Baltov, Bozhidar Borislavov 2D and 3D cultures of stem cell derived cardiac cells on patterned cell culture surfaces for cardiotox studies Steffen Hering Kampleitner, Carina Identifying the molecular and cellular pathways associated with bone fracture healing with and without biomaterials in healthy and osteoporotic bone Oskar Hoffmann, Klaus Wirth Karic, Medina Investigating Lysosomal Proteases in the Invasion and Metastasis of Pituitary Adenocarcinoma Mohammed Aufy Netzer, Michael Electrophysiological characterization and proof of principle cardiotoxicity screenings of cardioids Steffen Hering Nguyen, Van Phuong Potassium Kv10.1 Channel-Lipid Dysregulation in Diseases Anna Weinzinger Pasokh, Amir Targeting the gut-brain axis in hypertension-induced brain injury Marietta Zille Steshin, Ilia Developments of pharmacotherapies for GIRK linked diseases Anna Weinzinger Thivaios, Christos Athanasios Proteome-level identification of mechanism of action (MoA) of natural compounds Manuela Schmidt -
Division of Pharmacognosy
PhD student Thesis (working) title Supervisor(s) Bertaina, Lorenza Targeting RORγ(t) with natural and semisynthetic ligands Verena Dirsch Brenner, Martin The role of metabolic shifts for natural product-induced immunomodulation - Focus on Mass Spectrometry Elke Heiß, Wolfram Weckwerth Coffey, Christine Identifying Nature’s c(h)AMPions: Functional and mechanistic characterization of natural product derivatives as PDE4 inhibitors. Verena Dirsch, Alexander Perhal Gafriller, Johannes Judith Rollinger Haiss, Patricia Examination of the preventive/therapeutic potential of natural products in atherosclerotic and proliferative vascular wall changes using cell-based models Verena Dirsch Loukatou, Spyridoula Judith Rollinger Osswald, Xenia Targeting siderophore re-uptake as a strategy to fight infections caused by P. aeruginosa Sergey Zotchev Redl, Martina Identifying and dissecting health promoting natural products for healthy ageing in Caenorhabditis elegans Judith Rollinger Riffelsberger, Katharina Discovery and Characterisation of Natural Products as Ligands for Nuclear Receptors using Experimental and In Silico Approaches Verena Dirsch, Johannes Kirchmair Schranzer, Nicole Genome based discovery of novel natural products of Streptomyces bacteria from the Laxenburg pond sediment Sergey Zotchev Schuler, Eva Dissecting Metabolic Regulatory Mechanisms in Cancer Recurrence Karin Ortmayr Sosa Cabrera, Shara Natalia AMP(K)lifying Nrf2 - Digging into the fine‐tuned control of Nrf2‐mediated cellular responses by AMPK Elke Heiß Stenzl, Marlis Alrike Combined phenotypic and metabolome profiling for accelerated
compound characterizationKarin Ortmayr Theiler, Barbara Medicinal Plants against Diabetes Mellitus Search for New Antidiabetic Agents from Traditional Medicines Sabine Glasl-Tazreiter Waltenberger, Eva Judith Rollinger